BDBM347705 4-[(E)-1-(2-Chlorobenzoyl)-2- (dimethylamino)vinyloxy]-3-fluoro- benzonitrile ::US9790217, 28

SMILES: CN(C)\C=C(\Oc1ccc(cc1F)C#N)C(=O)c1ccccc1Cl

InChI Key: InChIKey=BUVOKCATNXSQII-GZTJUZNOSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 347705   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 11B1 (Homo sapiens (Human))	BDBM347705 (4-[(E)-1-(2-Chlorobenzoyl)-2- (dimethylamino)vinyl...) Show SMILES CN(C)\C=C(\Oc1ccc(cc1F)C#N)C(=O)c1ccccc1Cl Show InChI InChI=1S/C18H14ClFN2O2/c1-22(2)11-17(18(23)13-5-3-4-6-14(13)19)24-16-8-7-12(10-21)9-15(16)20/h3-9,11H,1-2H3/b17-11+	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.134	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...				US Patent US9790217 (2017) BindingDB Entry DOI: 10.7270/Q2K64M6M
					More data for this Ligand-Target Pair
Cytochrome P450 11B2 (CYP11B2) (Homo sapiens (Human))	BDBM347705 (4-[(E)-1-(2-Chlorobenzoyl)-2- (dimethylamino)vinyl...) Show SMILES CN(C)\C=C(\Oc1ccc(cc1F)C#N)C(=O)c1ccccc1Cl Show InChI InChI=1S/C18H14ClFN2O2/c1-22(2)11-17(18(23)13-5-3-4-6-14(13)19)24-16-8-7-12(10-21)9-15(16)20/h3-9,11H,1-2H3/b17-11+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.00200	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...				US Patent US9790217 (2017) BindingDB Entry DOI: 10.7270/Q2K64M6M
					More data for this Ligand-Target Pair