BDBM347713 4-[(Z)-1-(3-Benzyloxybenzoyl)-2- (dimethylamino)vinyloxy]benzonitrile::US9790217, 36
SMILES: CN(C)\C=C(/Oc1ccc(cc1)C#N)C(=O)c1cccc(OCc2ccccc2)c1
InChI Key: InChIKey=VYYYQFOQPKANFU-ULJHMMPZSA-N
Data: 2 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cytochrome P450 11B1 (Homo sapiens (Human)) | BDBM347713 (4-[(Z)-1-(3-Benzyloxybenzoyl)-2- (dimethylamino)vi...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 0.0530 | n/a | n/a | n/a | n/a |
Hoffmann-La Roche Inc. US Patent | Assay Description G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo... | US Patent US9790217 (2017) BindingDB Entry DOI: 10.7270/Q2K64M6M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 11B2 (CYP11B2) (Homo sapiens (Human)) | BDBM347713 (4-[(Z)-1-(3-Benzyloxybenzoyl)-2- (dimethylamino)vi...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 0.0170 | n/a | n/a | n/a | n/a |
Hoffmann-La Roche Inc. US Patent | Assay Description G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo... | US Patent US9790217 (2017) BindingDB Entry DOI: 10.7270/Q2K64M6M | |||||||||||
More data for this Ligand-Target Pair |