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SMILES: COC(=O)c1cccc(c1)C(=O)C(\Oc1ccc(cc1F)C#N)=C\N(C)C

InChI Key: InChIKey=LFXKALQIXFJREM-PDGQHHTCSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 347715   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 11B1, mitochondrial (Homo sapiens (Human))	BDBM347715 (Methyl 3-[(Z)-2-(4-cyano-2-fluoro- phenoxy)-3-(dim...) Show SMILES COC(=O)c1cccc(c1)C(=O)C(\Oc1ccc(cc1F)C#N)=C\N(C)C Show InChI InChI=1S/C20H17FN2O4/c1-23(2)12-18(27-17-8-7-13(11-22)9-16(17)21)19(24)14-5-4-6-15(10-14)20(25)26-3/h4-10,12H,1-3H3/b18-12-	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.321	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...				US Patent US9790217 (2017) BindingDB Entry DOI: 10.7270/Q2K64M6M
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM347715 (Methyl 3-[(Z)-2-(4-cyano-2-fluoro- phenoxy)-3-(dim...) Show SMILES COC(=O)c1cccc(c1)C(=O)C(\Oc1ccc(cc1F)C#N)=C\N(C)C Show InChI InChI=1S/C20H17FN2O4/c1-23(2)12-18(27-17-8-7-13(11-22)9-16(17)21)19(24)14-5-4-6-15(10-14)20(25)26-3/h4-10,12H,1-3H3/b18-12-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.0320	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...				US Patent US9790217 (2017) BindingDB Entry DOI: 10.7270/Q2K64M6M
					More data for this Ligand-Target Pair