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SMILES: Cn1nncc1COc1cccc(c1)-c1[nH]ncc1Oc1ccc(cc1)C#N

InChI Key: InChIKey=SSOXPDFOWLLROO-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 347730   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 11B1, mitochondrial (Homo sapiens (Human))	BDBM347730 (CHEM-US-00130 | US9790217, 53) Show SMILES Cn1nncc1COc1cccc(c1)-c1[nH]ncc1Oc1ccc(cc1)C#N Show InChI InChI=1S/C20H16N6O2/c1-26-16(11-23-25-26)13-27-18-4-2-3-15(9-18)20-19(12-22-24-20)28-17-7-5-14(10-21)6-8-17/h2-9,11-12H,13H2,1H3,(H,22,24)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.198	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...				US Patent US9790217 (2017) BindingDB Entry DOI: 10.7270/Q2K64M6M
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM347730 (CHEM-US-00130 | US9790217, 53) Show SMILES Cn1nncc1COc1cccc(c1)-c1[nH]ncc1Oc1ccc(cc1)C#N Show InChI InChI=1S/C20H16N6O2/c1-26-16(11-23-25-26)13-27-18-4-2-3-15(9-18)20-19(12-22-24-20)28-17-7-5-14(10-21)6-8-17/h2-9,11-12H,13H2,1H3,(H,22,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.0240	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...				US Patent US9790217 (2017) BindingDB Entry DOI: 10.7270/Q2K64M6M
					More data for this Ligand-Target Pair