BDBM347733 CHEM-US-00133::US9790217, 56

SMILES: Cn1cc(COc2cccc(c2)-c2[nH]ncc2Oc2ccc(cc2)C#N)cn1

InChI Key: InChIKey=JSZRTIATWONAHS-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 347733   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 11B1 (Homo sapiens (Human))	BDBM347733 (CHEM-US-00133 | US9790217, 56) Show SMILES Cn1cc(COc2cccc(c2)-c2[nH]ncc2Oc2ccc(cc2)C#N)cn1 Show InChI InChI=1S/C21H17N5O2/c1-26-13-16(11-24-26)14-27-19-4-2-3-17(9-19)21-20(12-23-25-21)28-18-7-5-15(10-22)6-8-18/h2-9,11-13H,14H2,1H3,(H,23,25)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.0940	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...				US Patent US9790217 (2017) BindingDB Entry DOI: 10.7270/Q2K64M6M
					More data for this Ligand-Target Pair
Cytochrome P450 11B2 (CYP11B2) (Homo sapiens (Human))	BDBM347733 (CHEM-US-00133 | US9790217, 56) Show SMILES Cn1cc(COc2cccc(c2)-c2[nH]ncc2Oc2ccc(cc2)C#N)cn1 Show InChI InChI=1S/C21H17N5O2/c1-26-13-16(11-24-26)14-27-19-4-2-3-17(9-19)21-20(12-23-25-21)28-18-7-5-15(10-22)6-8-18/h2-9,11-13H,14H2,1H3,(H,23,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.00900	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...				US Patent US9790217 (2017) BindingDB Entry DOI: 10.7270/Q2K64M6M
					More data for this Ligand-Target Pair