BDBM347757 CHEM-US-00174::US9790217, 79

SMILES: N#Cc1ccc(Oc2cn[nH]c2-c2ccccc2OCc2ccccn2)cc1

InChI Key: InChIKey=IPSBDZKNXWAZTN-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 347757   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 11B1 (Homo sapiens (Human))	BDBM347757 (CHEM-US-00174 | US9790217, 79) Show SMILES N#Cc1ccc(Oc2cn[nH]c2-c2ccccc2OCc2ccccn2)cc1 Show InChI InChI=1S/C22H16N4O2/c23-13-16-8-10-18(11-9-16)28-21-14-25-26-22(21)19-6-1-2-7-20(19)27-15-17-5-3-4-12-24-17/h1-12,14H,15H2,(H,25,26)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.00300	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...				US Patent US9790217 (2017) BindingDB Entry DOI: 10.7270/Q2K64M6M
					More data for this Ligand-Target Pair
Cytochrome P450 11B2 (CYP11B2) (Homo sapiens (Human))	BDBM347757 (CHEM-US-00174 | US9790217, 79) Show SMILES N#Cc1ccc(Oc2cn[nH]c2-c2ccccc2OCc2ccccn2)cc1 Show InChI InChI=1S/C22H16N4O2/c23-13-16-8-10-18(11-9-16)28-21-14-25-26-22(21)19-6-1-2-7-20(19)27-15-17-5-3-4-12-24-17/h1-12,14H,15H2,(H,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.000200	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...				US Patent US9790217 (2017) BindingDB Entry DOI: 10.7270/Q2K64M6M
					More data for this Ligand-Target Pair