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SMILES: Oc1cccc(-c2[nH]ncc2Oc2ccc(cc2)C#N)c1F

InChI Key: InChIKey=ILICJNIOKFHPQK-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 347762   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM347762 (4-[[3-(2-Fluoro-3-hydroxyphenyl)-1H-pyrazol-4-yl]o...) Show SMILES Oc1cccc(-c2[nH]ncc2Oc2ccc(cc2)C#N)c1F Show InChI InChI=1S/C16H10FN3O2/c17-15-12(2-1-3-13(15)21)16-14(9-19-20-16)22-11-6-4-10(8-18)5-7-11/h1-7,9,21H,(H,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.000400	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...				US Patent US9790217 (2017) BindingDB Entry DOI: 10.7270/Q2K64M6M
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Homo sapiens (Human))	BDBM347762 (4-[[3-(2-Fluoro-3-hydroxyphenyl)-1H-pyrazol-4-yl]o...) Show SMILES Oc1cccc(-c2[nH]ncc2Oc2ccc(cc2)C#N)c1F Show InChI InChI=1S/C16H10FN3O2/c17-15-12(2-1-3-13(15)21)16-14(9-19-20-16)22-11-6-4-10(8-18)5-7-11/h1-7,9,21H,(H,19,20)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.0170	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...				US Patent US9790217 (2017) BindingDB Entry DOI: 10.7270/Q2K64M6M
					More data for this Ligand-Target Pair