null

SMILES: CN1CCN(CC1)c1nc2ccccc2cc1Cn1nc(-c2ccc3cc(N)sc3c2)c2c(N)ccnc12

InChI Key: InChIKey=ANRBNTMAAZLQLH-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 348161   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM348161 (US9790228, Compound 80) Show SMILES CN1CCN(CC1)c1nc2ccccc2cc1Cn1nc(-c2ccc3cc(N)sc3c2)c2c(N)ccnc12 Show InChI InChI=1S/C29H28N8S/c1-35-10-12-36(13-11-35)28-21(14-18-4-2-3-5-23(18)33-28)17-37-29-26(22(30)8-9-32-29)27(34-37)20-7-6-19-16-25(31)38-24(19)15-20/h2-9,14-16H,10-13,17,31H2,1H3,(H2,30,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Intellikine LLC US Patent					Assay Description Class I PI3-Ks can be either purchased (p110α/p85α, p110β/p85α, p110δ/p85α from Upstate, and p110γ from Sigma) or ...				US Patent US9790228 (2017) BindingDB Entry DOI: 10.7270/Q26112FV
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta (Homo sapiens (Human))	BDBM348161 (US9790228, Compound 80) Show SMILES CN1CCN(CC1)c1nc2ccccc2cc1Cn1nc(-c2ccc3cc(N)sc3c2)c2c(N)ccnc12 Show InChI InChI=1S/C29H28N8S/c1-35-10-12-36(13-11-35)28-21(14-18-4-2-3-5-23(18)33-28)17-37-29-26(22(30)8-9-32-29)27(34-37)20-7-6-19-16-25(31)38-24(19)15-20/h2-9,14-16H,10-13,17,31H2,1H3,(H2,30,32)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Intellikine LLC US Patent					Assay Description Class I PI3-Ks can be either purchased (p110α/p85α, p110β/p85α, p110δ/p85α from Upstate, and p110γ from Sigma) or ...				US Patent US9790228 (2017) BindingDB Entry DOI: 10.7270/Q26112FV
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha (Homo sapiens (Human))	BDBM348161 (US9790228, Compound 80) Show SMILES CN1CCN(CC1)c1nc2ccccc2cc1Cn1nc(-c2ccc3cc(N)sc3c2)c2c(N)ccnc12 Show InChI InChI=1S/C29H28N8S/c1-35-10-12-36(13-11-35)28-21(14-18-4-2-3-5-23(18)33-28)17-37-29-26(22(30)8-9-32-29)27(34-37)20-7-6-19-16-25(31)38-24(19)15-20/h2-9,14-16H,10-13,17,31H2,1H3,(H2,30,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Intellikine LLC US Patent					Assay Description Class I PI3-Ks can be either purchased (p110α/p85α, p110β/p85α, p110δ/p85α from Upstate, and p110γ from Sigma) or ...				US Patent US9790228 (2017) BindingDB Entry DOI: 10.7270/Q26112FV
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM348161 (US9790228, Compound 80) Show SMILES CN1CCN(CC1)c1nc2ccccc2cc1Cn1nc(-c2ccc3cc(N)sc3c2)c2c(N)ccnc12 Show InChI InChI=1S/C29H28N8S/c1-35-10-12-36(13-11-35)28-21(14-18-4-2-3-5-23(18)33-28)17-37-29-26(22(30)8-9-32-29)27(34-37)20-7-6-19-16-25(31)38-24(19)15-20/h2-9,14-16H,10-13,17,31H2,1H3,(H2,30,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Intellikine LLC US Patent					Assay Description Class I PI3-Ks can be either purchased (p110α/p85α, p110β/p85α, p110δ/p85α from Upstate, and p110γ from Sigma) or ...				US Patent US9790228 (2017) BindingDB Entry DOI: 10.7270/Q26112FV
					More data for this Ligand-Target Pair