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SMILES: CCc1nc2ccccc2cc1Cn1nc(-c2cc(O)cc(F)c2)c2c(N)ncnc12

InChI Key: InChIKey=RMUZZRFEYODKHJ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 348178   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM348178 (US9790228, Compound 97) Show SMILES CCc1nc2ccccc2cc1Cn1nc(-c2cc(O)cc(F)c2)c2c(N)ncnc12 Show InChI InChI=1S/C23H19FN6O/c1-2-18-15(7-13-5-3-4-6-19(13)28-18)11-30-23-20(22(25)26-12-27-23)21(29-30)14-8-16(24)10-17(31)9-14/h3-10,12,31H,2,11H2,1H3,(H2,25,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Intellikine LLC US Patent					Assay Description Class I PI3-Ks can be either purchased (p110α/p85α, p110β/p85α, p110δ/p85α from Upstate, and p110γ from Sigma) or ...				US Patent US9790228 (2017) BindingDB Entry DOI: 10.7270/Q26112FV
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta (Homo sapiens (Human))	BDBM348178 (US9790228, Compound 97) Show SMILES CCc1nc2ccccc2cc1Cn1nc(-c2cc(O)cc(F)c2)c2c(N)ncnc12 Show InChI InChI=1S/C23H19FN6O/c1-2-18-15(7-13-5-3-4-6-19(13)28-18)11-30-23-20(22(25)26-12-27-23)21(29-30)14-8-16(24)10-17(31)9-14/h3-10,12,31H,2,11H2,1H3,(H2,25,26,27)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Intellikine LLC US Patent					Assay Description Class I PI3-Ks can be either purchased (p110α/p85α, p110β/p85α, p110δ/p85α from Upstate, and p110γ from Sigma) or ...				US Patent US9790228 (2017) BindingDB Entry DOI: 10.7270/Q26112FV
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha (Homo sapiens (Human))	BDBM348178 (US9790228, Compound 97) Show SMILES CCc1nc2ccccc2cc1Cn1nc(-c2cc(O)cc(F)c2)c2c(N)ncnc12 Show InChI InChI=1S/C23H19FN6O/c1-2-18-15(7-13-5-3-4-6-19(13)28-18)11-30-23-20(22(25)26-12-27-23)21(29-30)14-8-16(24)10-17(31)9-14/h3-10,12,31H,2,11H2,1H3,(H2,25,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Intellikine LLC US Patent					Assay Description Class I PI3-Ks can be either purchased (p110α/p85α, p110β/p85α, p110δ/p85α from Upstate, and p110γ from Sigma) or ...				US Patent US9790228 (2017) BindingDB Entry DOI: 10.7270/Q26112FV
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM348178 (US9790228, Compound 97) Show SMILES CCc1nc2ccccc2cc1Cn1nc(-c2cc(O)cc(F)c2)c2c(N)ncnc12 Show InChI InChI=1S/C23H19FN6O/c1-2-18-15(7-13-5-3-4-6-19(13)28-18)11-30-23-20(22(25)26-12-27-23)21(29-30)14-8-16(24)10-17(31)9-14/h3-10,12,31H,2,11H2,1H3,(H2,25,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Intellikine LLC US Patent					Assay Description Class I PI3-Ks can be either purchased (p110α/p85α, p110β/p85α, p110δ/p85α from Upstate, and p110γ from Sigma) or ...				US Patent US9790228 (2017) BindingDB Entry DOI: 10.7270/Q26112FV
					More data for this Ligand-Target Pair