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SMILES: Nc1ncc2cc(ccc2n1)-c1nn(Cc2cc3ccccc3nc2N2CCOCC2)c2ncnc(N)c12

InChI Key: InChIKey=FCXAOIXQFWWVHY-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 348220   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM348220 (US9790228, Compound 139) Show SMILES Nc1ncc2cc(ccc2n1)-c1nn(Cc2cc3ccccc3nc2N2CCOCC2)c2ncnc(N)c12 Show InChI InChI=1S/C27H24N10O/c28-24-22-23(17-5-6-21-18(12-17)13-30-27(29)34-21)35-37(26(22)32-15-31-24)14-19-11-16-3-1-2-4-20(16)33-25(19)36-7-9-38-10-8-36/h1-6,11-13,15H,7-10,14H2,(H2,28,31,32)(H2,29,30,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Intellikine LLC US Patent					Assay Description Class I PI3-Ks can be either purchased (p110α/p85α, p110β/p85α, p110δ/p85α from Upstate, and p110γ from Sigma) or ...				US Patent US9790228 (2017) BindingDB Entry DOI: 10.7270/Q26112FV
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta (Homo sapiens (Human))	BDBM348220 (US9790228, Compound 139) Show SMILES Nc1ncc2cc(ccc2n1)-c1nn(Cc2cc3ccccc3nc2N2CCOCC2)c2ncnc(N)c12 Show InChI InChI=1S/C27H24N10O/c28-24-22-23(17-5-6-21-18(12-17)13-30-27(29)34-21)35-37(26(22)32-15-31-24)14-19-11-16-3-1-2-4-20(16)33-25(19)36-7-9-38-10-8-36/h1-6,11-13,15H,7-10,14H2,(H2,28,31,32)(H2,29,30,34)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Intellikine LLC US Patent					Assay Description Class I PI3-Ks can be either purchased (p110α/p85α, p110β/p85α, p110δ/p85α from Upstate, and p110γ from Sigma) or ...				US Patent US9790228 (2017) BindingDB Entry DOI: 10.7270/Q26112FV
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha (Homo sapiens (Human))	BDBM348220 (US9790228, Compound 139) Show SMILES Nc1ncc2cc(ccc2n1)-c1nn(Cc2cc3ccccc3nc2N2CCOCC2)c2ncnc(N)c12 Show InChI InChI=1S/C27H24N10O/c28-24-22-23(17-5-6-21-18(12-17)13-30-27(29)34-21)35-37(26(22)32-15-31-24)14-19-11-16-3-1-2-4-20(16)33-25(19)36-7-9-38-10-8-36/h1-6,11-13,15H,7-10,14H2,(H2,28,31,32)(H2,29,30,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Intellikine LLC US Patent					Assay Description Class I PI3-Ks can be either purchased (p110α/p85α, p110β/p85α, p110δ/p85α from Upstate, and p110γ from Sigma) or ...				US Patent US9790228 (2017) BindingDB Entry DOI: 10.7270/Q26112FV
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM348220 (US9790228, Compound 139) Show SMILES Nc1ncc2cc(ccc2n1)-c1nn(Cc2cc3ccccc3nc2N2CCOCC2)c2ncnc(N)c12 Show InChI InChI=1S/C27H24N10O/c28-24-22-23(17-5-6-21-18(12-17)13-30-27(29)34-21)35-37(26(22)32-15-31-24)14-19-11-16-3-1-2-4-20(16)33-25(19)36-7-9-38-10-8-36/h1-6,11-13,15H,7-10,14H2,(H2,28,31,32)(H2,29,30,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Intellikine LLC US Patent					Assay Description Class I PI3-Ks can be either purchased (p110α/p85α, p110β/p85α, p110δ/p85α from Upstate, and p110γ from Sigma) or ...				US Patent US9790228 (2017) BindingDB Entry DOI: 10.7270/Q26112FV
					More data for this Ligand-Target Pair