BDBM34823 (3-chloro-5-ethoxy-4-methoxy-benzyl)-(4-pyrrolidinophenyl)amine::MLS000702067::N-(3-chloro-5-ethoxy-4-methoxybenzyl)-N-[4-(1-pyrrolidinyl)phenyl]amine::N-[(3-chloranyl-5-ethoxy-4-methoxy-phenyl)methyl]-4-pyrrolidin-1-yl-aniline::N-[(3-chloro-5-ethoxy-4-methoxyphenyl)methyl]-4-(1-pyrrolidinyl)aniline::N-[(3-chloro-5-ethoxy-4-methoxyphenyl)methyl]-4-pyrrolidin-1-ylaniline::SMR000230096::cid_979664

SMILES: CCOc1cc(CNc2ccc(cc2)N2CCCC2)cc(Cl)c1OC

InChI Key: InChIKey=QQWGJAPOKIMOPE-UHFFFAOYSA-N

Data: 12 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 34823   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MPI protein (Homo sapiens (Human))	BDBM34823 ((3-chloro-5-ethoxy-4-methoxy-benzyl)-(4-pyrrolidin...) Show SMILES CCOc1cc(CNc2ccc(cc2)N2CCCC2)cc(Cl)c1OC Show InChI InChI=1S/C20H25ClN2O2/c1-3-25-19-13-15(12-18(21)20(19)24-2)14-22-16-6-8-17(9-7-16)23-10-4-5-11-23/h6-9,12-13,22H,3-5,10-11,14H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	8.91E+3	n/a	n/a	n/a	n/a	7.4	23
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description The purpose of this assay is to identify non-competititve inhibitors of human PMI. This is accomplished by using a G6PD- NADPH-coupled assay. In the ...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2CF9NFM
					More data for this Ligand-Target Pair
YopH (Yersinia enterocolitica)	BDBM34823 ((3-chloro-5-ethoxy-4-methoxy-benzyl)-(4-pyrrolidin...) Show SMILES CCOc1cc(CNc2ccc(cc2)N2CCCC2)cc(Cl)c1OC Show InChI InChI=1S/C20H25ClN2O2/c1-3-25-19-13-15(12-18(21)20(19)24-2)14-22-16-6-8-17(9-7-16)23-10-4-5-11-23/h6-9,12-13,22H,3-5,10-11,14H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Molecular Library Screening Center Curated by PubChem BioAssay					Assay Description Yersinia pestis is the causal agent of the bubonic plague and, although modern antibiotics are extremely effective against the malady, the plague rem...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2C24TVC
					More data for this Ligand-Target Pair
YopH (Yersinia enterocolitica)	BDBM34823 ((3-chloro-5-ethoxy-4-methoxy-benzyl)-(4-pyrrolidin...) Show SMILES CCOc1cc(CNc2ccc(cc2)N2CCCC2)cc(Cl)c1OC Show InChI InChI=1S/C20H25ClN2O2/c1-3-25-19-13-15(12-18(21)20(19)24-2)14-22-16-6-8-17(9-7-16)23-10-4-5-11-23/h6-9,12-13,22H,3-5,10-11,14H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Molecular Library Screening Center Curated by PubChem BioAssay					Assay Description Yersinia pestis is the causal agent of the bubonic plague and, although modern antibiotics are extremely effective against the malady, the plague rem...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2794330
					More data for this Ligand-Target Pair
YopH (Yersinia enterocolitica)	BDBM34823 ((3-chloro-5-ethoxy-4-methoxy-benzyl)-(4-pyrrolidin...) Show SMILES CCOc1cc(CNc2ccc(cc2)N2CCCC2)cc(Cl)c1OC Show InChI InChI=1S/C20H25ClN2O2/c1-3-25-19-13-15(12-18(21)20(19)24-2)14-22-16-6-8-17(9-7-16)23-10-4-5-11-23/h6-9,12-13,22H,3-5,10-11,14H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Molecular Library Screening Center Curated by PubChem BioAssay					Assay Description Yersinia pestis is the causal agent of the bubonic plague and, although modern antibiotics are extremely effective against the malady, the plague rem...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2GT5KKS
					More data for this Ligand-Target Pair
eukaryotic translation initiation factor 4 gamma, 1 isoform 4 (Homo sapiens (Human))	BDBM34823 ((3-chloro-5-ethoxy-4-methoxy-benzyl)-(4-pyrrolidin...) Show SMILES CCOc1cc(CNc2ccc(cc2)N2CCCC2)cc(Cl)c1OC Show InChI InChI=1S/C20H25ClN2O2/c1-3-25-19-13-15(12-18(21)20(19)24-2)14-22-16-6-8-17(9-7-16)23-10-4-5-11-23/h6-9,12-13,22H,3-5,10-11,14H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	6.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Molecular Libraries Screening Center Curated by PubChem BioAssay					Assay Description Dose Response Confirmation for Small Molecule Inhibitors of Eukaryotic Translation Initiation NIH Molecular Libraries Screening Centers Network [MLSC...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2RN3686
					More data for this Ligand-Target Pair
Apoptotic peptidase activating factor 1 (Homo sapiens (Human))	BDBM34823 ((3-chloro-5-ethoxy-4-methoxy-benzyl)-(4-pyrrolidin...) Show SMILES CCOc1cc(CNc2ccc(cc2)N2CCCC2)cc(Cl)c1OC Show InChI InChI=1S/C20H25ClN2O2/c1-3-25-19-13-15(12-18(21)20(19)24-2)14-22-16-6-8-17(9-7-16)23-10-4-5-11-23/h6-9,12-13,22H,3-5,10-11,14H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBIMR, San Diego, C...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q2F18X8S
					More data for this Ligand-Target Pair
Glucose 6-phosphate dehydrogenase (G6PD) (Homo sapiens (Human))	BDBM34823 ((3-chloro-5-ethoxy-4-methoxy-benzyl)-(4-pyrrolidin...) Show SMILES CCOc1cc(CNc2ccc(cc2)N2CCCC2)cc(Cl)c1OC Show InChI InChI=1S/C20H25ClN2O2/c1-3-25-19-13-15(12-18(21)20(19)24-2)14-22-16-6-8-17(9-7-16)23-10-4-5-11-23/h6-9,12-13,22H,3-5,10-11,14H2,1-2H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>8.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego CA...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q2V12389
					More data for this Ligand-Target Pair
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase (Plasmodium falciparum 3D7)	BDBM34823 ((3-chloro-5-ethoxy-4-methoxy-benzyl)-(4-pyrrolidin...) Show SMILES CCOc1cc(CNc2ccc(cc2)N2CCCC2)cc(Cl)c1OC Show InChI InChI=1S/C20H25ClN2O2/c1-3-25-19-13-15(12-18(21)20(19)24-2)14-22-16-6-8-17(9-7-16)23-10-4-5-11-23/h6-9,12-13,22H,3-5,10-11,14H2,1-2H3	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	3.87E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego CA...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q2ZS2TZG
					More data for this Ligand-Target Pair
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase (Plasmodium falciparum 3D7)	BDBM34823 ((3-chloro-5-ethoxy-4-methoxy-benzyl)-(4-pyrrolidin...) Show SMILES CCOc1cc(CNc2ccc(cc2)N2CCCC2)cc(Cl)c1OC Show InChI InChI=1S/C20H25ClN2O2/c1-3-25-19-13-15(12-18(21)20(19)24-2)14-22-16-6-8-17(9-7-16)23-10-4-5-11-23/h6-9,12-13,22H,3-5,10-11,14H2,1-2H3	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>8.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego CA...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q27H1H3W
					More data for this Ligand-Target Pair
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase (Plasmodium falciparum 3D7)	BDBM34823 ((3-chloro-5-ethoxy-4-methoxy-benzyl)-(4-pyrrolidin...) Show SMILES CCOc1cc(CNc2ccc(cc2)N2CCCC2)cc(Cl)c1OC Show InChI InChI=1S/C20H25ClN2O2/c1-3-25-19-13-15(12-18(21)20(19)24-2)14-22-16-6-8-17(9-7-16)23-10-4-5-11-23/h6-9,12-13,22H,3-5,10-11,14H2,1-2H3	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>8.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego CA...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q23T9FQ1
					More data for this Ligand-Target Pair
Apoptotic peptidase activating factor 1 (Homo sapiens (Human))	BDBM34823 ((3-chloro-5-ethoxy-4-methoxy-benzyl)-(4-pyrrolidin...) Show SMILES CCOc1cc(CNc2ccc(cc2)N2CCCC2)cc(Cl)c1OC Show InChI InChI=1S/C20H25ClN2O2/c1-3-25-19-13-15(12-18(21)20(19)24-2)14-22-16-6-8-17(9-7-16)23-10-4-5-11-23/h6-9,12-13,22H,3-5,10-11,14H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBIMR, San Diego, C...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q2JS9NZB
					More data for this Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1 (Homo sapiens (Human))	BDBM34823 ((3-chloro-5-ethoxy-4-methoxy-benzyl)-(4-pyrrolidin...) Show SMILES CCOc1cc(CNc2ccc(cc2)N2CCCC2)cc(Cl)c1OC Show InChI InChI=1S/C20H25ClN2O2/c1-3-25-19-13-15(12-18(21)20(19)24-2)14-22-16-6-8-17(9-7-16)23-10-4-5-11-23/h6-9,12-13,22H,3-5,10-11,14H2,1-2H3	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	2.43E+3	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Molecular Libraries Screening Center Curated by PubChem BioAssay					Assay Description NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Nikolovska-Coleska, Univer...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q23X8539
					More data for this Ligand-Target Pair