null

SMILES: CC(C)N(C)c1nc2ccccc2cc1Cn1nc(-c2ccc3nc(NC(C)=O)sc3c2)c2c(N)ncnc12

InChI Key: InChIKey=NRAJEVQFTLCPNU-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 348232   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM348232 (US9790228, Compound 151) Show SMILES CC(C)N(C)c1nc2ccccc2cc1Cn1nc(-c2ccc3nc(NC(C)=O)sc3c2)c2c(N)ncnc12 Show InChI InChI=1S/C28H27N9OS/c1-15(2)36(4)26-19(11-17-7-5-6-8-20(17)33-26)13-37-27-23(25(29)30-14-31-27)24(35-37)18-9-10-21-22(12-18)39-28(34-21)32-16(3)38/h5-12,14-15H,13H2,1-4H3,(H2,29,30,31)(H,32,34,38)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Intellikine LLC US Patent					Assay Description Class I PI3-Ks can be either purchased (p110α/p85α, p110β/p85α, p110δ/p85α from Upstate, and p110γ from Sigma) or ...				US Patent US9790228 (2017) BindingDB Entry DOI: 10.7270/Q26112FV
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta (Homo sapiens (Human))	BDBM348232 (US9790228, Compound 151) Show SMILES CC(C)N(C)c1nc2ccccc2cc1Cn1nc(-c2ccc3nc(NC(C)=O)sc3c2)c2c(N)ncnc12 Show InChI InChI=1S/C28H27N9OS/c1-15(2)36(4)26-19(11-17-7-5-6-8-20(17)33-26)13-37-27-23(25(29)30-14-31-27)24(35-37)18-9-10-21-22(12-18)39-28(34-21)32-16(3)38/h5-12,14-15H,13H2,1-4H3,(H2,29,30,31)(H,32,34,38)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Intellikine LLC US Patent					Assay Description Class I PI3-Ks can be either purchased (p110α/p85α, p110β/p85α, p110δ/p85α from Upstate, and p110γ from Sigma) or ...				US Patent US9790228 (2017) BindingDB Entry DOI: 10.7270/Q26112FV
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM348232 (US9790228, Compound 151) Show SMILES CC(C)N(C)c1nc2ccccc2cc1Cn1nc(-c2ccc3nc(NC(C)=O)sc3c2)c2c(N)ncnc12 Show InChI InChI=1S/C28H27N9OS/c1-15(2)36(4)26-19(11-17-7-5-6-8-20(17)33-26)13-37-27-23(25(29)30-14-31-27)24(35-37)18-9-10-21-22(12-18)39-28(34-21)32-16(3)38/h5-12,14-15H,13H2,1-4H3,(H2,29,30,31)(H,32,34,38)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Intellikine LLC US Patent					Assay Description Class I PI3-Ks can be either purchased (p110α/p85α, p110β/p85α, p110δ/p85α from Upstate, and p110γ from Sigma) or ...				US Patent US9790228 (2017) BindingDB Entry DOI: 10.7270/Q26112FV
					More data for this Ligand-Target Pair