null

SMILES: CC(C)N1CCN(CC1)c1nc2ccccc2cc1Cn1nc(-c2ccc3nc(NC(C)=O)sc3c2)c2c(N)ncnc12

InChI Key: InChIKey=JUVRHEPTYJHZCN-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 348244   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta (Homo sapiens (Human))	BDBM348244 (US9790228, Compound 163) Show SMILES CC(C)N1CCN(CC1)c1nc2ccccc2cc1Cn1nc(-c2ccc3nc(NC(C)=O)sc3c2)c2c(N)ncnc12 Show InChI InChI=1S/C31H32N10OS/c1-18(2)39-10-12-40(13-11-39)29-22(14-20-6-4-5-7-23(20)36-29)16-41-30-26(28(32)33-17-34-30)27(38-41)21-8-9-24-25(15-21)43-31(37-24)35-19(3)42/h4-9,14-15,17-18H,10-13,16H2,1-3H3,(H2,32,33,34)(H,35,37,42)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Intellikine LLC US Patent					Assay Description Class I PI3-Ks can be either purchased (p110α/p85α, p110β/p85α, p110δ/p85α from Upstate, and p110γ from Sigma) or ...				US Patent US9790228 (2017) BindingDB Entry DOI: 10.7270/Q26112FV
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha (Homo sapiens (Human))	BDBM348244 (US9790228, Compound 163) Show SMILES CC(C)N1CCN(CC1)c1nc2ccccc2cc1Cn1nc(-c2ccc3nc(NC(C)=O)sc3c2)c2c(N)ncnc12 Show InChI InChI=1S/C31H32N10OS/c1-18(2)39-10-12-40(13-11-39)29-22(14-20-6-4-5-7-23(20)36-29)16-41-30-26(28(32)33-17-34-30)27(38-41)21-8-9-24-25(15-21)43-31(37-24)35-19(3)42/h4-9,14-15,17-18H,10-13,16H2,1-3H3,(H2,32,33,34)(H,35,37,42)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Intellikine LLC US Patent					Assay Description Class I PI3-Ks can be either purchased (p110α/p85α, p110β/p85α, p110δ/p85α from Upstate, and p110γ from Sigma) or ...				US Patent US9790228 (2017) BindingDB Entry DOI: 10.7270/Q26112FV
					More data for this Ligand-Target Pair