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BDBM34997 benzothienopyrimidinone deriv., 6n

SMILES: Oc1cccc(NCc2nc3c4cc(Cl)ccc4sc3c(=O)[nH]2)c1

InChI Key: InChIKey=RLPCQQSZTQVWAR-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 34997   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serine/threonine-protein kinase PIM


(Homo sapiens (Human))
BDBM34997
PNG
(benzothienopyrimidinone deriv., 6n)
Show SMILES Oc1cccc(NCc2nc3c4cc(Cl)ccc4sc3c(=O)[nH]2)c1
Show InChI InChI=1S/C17H12ClN3O2S/c18-9-4-5-13-12(6-9)15-16(24-13)17(23)21-14(20-15)8-19-10-2-1-3-11(22)7-10/h1-7,19,22H,8H2,(H,20,21,23)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
0.900 -12.2n/an/an/an/an/a7.523



Abbott Laboratories



Assay Description
In 384-well v-bottom polypropylene plates, compound (2% DMSO) was mixed with Pim kinase and peptide substrate, followed by immediate initiation with ...


J Med Chem 52: 6621-36 (2009)


Article DOI: 10.1021/jm900943h
BindingDB Entry DOI: 10.7270/Q27P8WQW
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase pim-2


(Homo sapiens (Human))
BDBM34997
PNG
(benzothienopyrimidinone deriv., 6n)
Show SMILES Oc1cccc(NCc2nc3c4cc(Cl)ccc4sc3c(=O)[nH]2)c1
Show InChI InChI=1S/C17H12ClN3O2S/c18-9-4-5-13-12(6-9)15-16(24-13)17(23)21-14(20-15)8-19-10-2-1-3-11(22)7-10/h1-7,19,22H,8H2,(H,20,21,23)
PDB
MMDB

KEGG

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
147 -9.31n/an/an/an/an/an/a25



Abbott Laboratories



Assay Description
In 384-well v-bottom polypropylene plates, compound (2% DMSO) was mixed with Pim kinase and peptide substrate, followed by immediate initiation with ...


J Med Chem 52: 6621-36 (2009)


Article DOI: 10.1021/jm900943h
BindingDB Entry DOI: 10.7270/Q27P8WQW
More data for this
Ligand-Target Pair