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BDBM350051 US10208024, Example 50

SMILES: COc1cc(OC)cc(c1)-n1nc(cc(C)c1=O)-c1nc(cnc1N)-c1cnn(c1)C1CCNCC1

InChI Key:

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 350051   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
VEGF-receptor 2 and Fibroblast growth factor receptor 1


(Homo sapiens (Human))
BDBM350051
PNG
(US10208024, Example 50)
Show SMILES COc1cc(OC)cc(c1)-n1nc(cc(C)c1=O)-c1nc(cnc1N)-c1cnn(c1)C1CCNCC1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
US Patent
n/an/a 3.5n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent




US Patent US10208024 (2019)


Article DOI: 10.1016/j.bmcl.2004.06.019
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor


(Homo sapiens (Human))
BDBM350051
PNG
(US10208024, Example 50)
Show SMILES COc1cc(OC)cc(c1)-n1nc(cc(C)c1=O)-c1nc(cnc1N)-c1cnn(c1)C1CCNCC1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
US Patent
n/an/a 1.80n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent




US Patent US10208024 (2019)


Article DOI: 10.1016/j.bmcl.2004.06.019
More data for this
Ligand-Target Pair
VEGF-receptor 2 and Fibroblast growth factor receptor 2


(Homo sapiens (Human))
BDBM350051
PNG
(US10208024, Example 50)
Show SMILES COc1cc(OC)cc(c1)-n1nc(cc(C)c1=O)-c1nc(cnc1N)-c1cnn(c1)C1CCNCC1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
US Patent
n/an/a 0.900n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent




US Patent US10208024 (2019)


Article DOI: 10.1016/j.bmcl.2004.06.019
More data for this
Ligand-Target Pair