BDBM35015 benzothienopyrimidinone deriv., 13c

SMILES: CN(C)Cc1nc2c3cc(ccc3sc2c(=O)[nH]1)C#CCCCCN1CCCCC1

InChI Key: InChIKey=KEGTZWAXCSFQBQ-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 35015   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM35015 (benzothienopyrimidinone deriv., 13c) Show SMILES CN(C)Cc1nc2c3cc(ccc3sc2c(=O)[nH]1)C#CCCCCN1CCCCC1 Show InChI InChI=1S/C24H30N4OS/c1-27(2)17-21-25-22-19-16-18(11-12-20(19)30-23(22)24(29)26-21)10-6-3-4-7-13-28-14-8-5-9-15-28/h11-12,16H,3-5,7-9,13-15,17H2,1-2H3,(H,25,26,29)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	3	-11.6	n/a	n/a	n/a	n/a	n/a	n/a	25
Abbott Laboratories					Assay Description In 384-well v-bottom polypropylene plates, compound (2% DMSO) was mixed with Pim kinase and peptide substrate, followed by immediate initiation with ...				J Med Chem 52: 6621-36 (2009) Article DOI: 10.1021/jm900943h BindingDB Entry DOI: 10.7270/Q27P8WQW
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM35015 (benzothienopyrimidinone deriv., 13c) Show SMILES CN(C)Cc1nc2c3cc(ccc3sc2c(=O)[nH]1)C#CCCCCN1CCCCC1 Show InChI InChI=1S/C24H30N4OS/c1-27(2)17-21-25-22-19-16-18(11-12-20(19)30-23(22)24(29)26-21)10-6-3-4-7-13-28-14-8-5-9-15-28/h11-12,16H,3-5,7-9,13-15,17H2,1-2H3,(H,25,26,29)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	23	-10.4	n/a	n/a	n/a	n/a	n/a	n/a	25
Abbott Laboratories					Assay Description In 384-well v-bottom polypropylene plates, compound (2% DMSO) was mixed with Pim kinase and peptide substrate, followed by immediate initiation with ...				J Med Chem 52: 6621-36 (2009) Article DOI: 10.1021/jm900943h BindingDB Entry DOI: 10.7270/Q27P8WQW
					More data for this Ligand-Target Pair