BDBM350197 US10208056, Compound 29

SMILES: CC1(C)Oc2cnccc2-c2[nH]c(C(O)=O)c(Br)c12

InChI Key: InChIKey=ZHJUEEVXBXXRCT-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 350197   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-C/Cyclin-dependent kinase 8 (Homo sapiens (Human))	BDBM350197 (US10208056, Compound 29) Show SMILES CC1(C)Oc2cnccc2-c2[nH]c(C(O)=O)c(Br)c12 Show InChI InChI=1S/C13H11BrN2O3/c1-13(2)8-9(14)11(12(17)18)16-10(8)6-3-4-15-5-7(6)19-13/h3-5,16H,1-2H3,(H,17,18)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	52.5	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN DEL SECTOR PÚBLICO ESTATAL CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS CARLOS III (F.S.P. CNIO) US Patent					Assay Description The binding assay relies on the LanthaScreen™ Eu-Kinase Binding Assay (Invitrogen. This is a kinase assay platform based on measuring the binding and...				US Patent US10208056 (2019) BindingDB Entry DOI: 10.7270/Q2GB266B
					More data for this Ligand-Target Pair
Cyclin-C/Cyclin-dependent kinase 19 (Homo sapiens (Human))	BDBM350197 (US10208056, Compound 29) Show SMILES CC1(C)Oc2cnccc2-c2[nH]c(C(O)=O)c(Br)c12 Show InChI InChI=1S/C13H11BrN2O3/c1-13(2)8-9(14)11(12(17)18)16-10(8)6-3-4-15-5-7(6)19-13/h3-5,16H,1-2H3,(H,17,18)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	205	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN DEL SECTOR PÚBLICO ESTATAL CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS CARLOS III (F.S.P. CNIO) US Patent					Assay Description The binding assay relies on the LanthaScreen™ Eu-Kinase Binding Assay (Invitrogen). This is a kinase assay platform based on measuring the binding an...				US Patent US10208056 (2019) BindingDB Entry DOI: 10.7270/Q2GB266B
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase haspin (Homo sapiens (Human))	BDBM350197 (US10208056, Compound 29) Show SMILES CC1(C)Oc2cnccc2-c2[nH]c(C(O)=O)c(Br)c12 Show InChI InChI=1S/C13H11BrN2O3/c1-13(2)8-9(14)11(12(17)18)16-10(8)6-3-4-15-5-7(6)19-13/h3-5,16H,1-2H3,(H,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	89.3	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN DEL SECTOR PÚBLICO ESTATAL CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS CARLOS III (F.S.P. CNIO) US Patent					Assay Description The kinase assay relies on ADP-GloKM biochemical kinase assay (Promega). This is a luminescent kinase assay that measures ADP formed from a kinase re...				US Patent US10208056 (2019) BindingDB Entry DOI: 10.7270/Q2GB266B
					More data for this Ligand-Target Pair