null

SMILES: CC1(C)Oc2cnccc2-c2[nH]c(C(O)=O)c(c12)-c1ccc(cc1)S(N)(=O)=O

InChI Key: InChIKey=RTYCSOHJUAWUAK-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 350198   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-C/Cyclin-dependent kinase 8 (Homo sapiens (Human))	BDBM350198 (US10208056, Compound 30) Show SMILES CC1(C)Oc2cnccc2-c2[nH]c(C(O)=O)c(c12)-c1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C19H17N3O5S/c1-19(2)15-14(10-3-5-11(6-4-10)28(20,25)26)17(18(23)24)22-16(15)12-7-8-21-9-13(12)27-19/h3-9,22H,1-2H3,(H,23,24)(H2,20,25,26)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8.94	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN DEL SECTOR PÚBLICO ESTATAL CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS CARLOS III (F.S.P. CNIO) US Patent					Assay Description The binding assay relies on the LanthaScreen™ Eu-Kinase Binding Assay (Invitrogen. This is a kinase assay platform based on measuring the binding and...				US Patent US10208056 (2019) BindingDB Entry DOI: 10.7270/Q2GB266B
					More data for this Ligand-Target Pair
Cyclin-C/Cyclin-dependent kinase 19 (Homo sapiens (Human))	BDBM350198 (US10208056, Compound 30) Show SMILES CC1(C)Oc2cnccc2-c2[nH]c(C(O)=O)c(c12)-c1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C19H17N3O5S/c1-19(2)15-14(10-3-5-11(6-4-10)28(20,25)26)17(18(23)24)22-16(15)12-7-8-21-9-13(12)27-19/h3-9,22H,1-2H3,(H,23,24)(H2,20,25,26)	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20.7	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN DEL SECTOR PÚBLICO ESTATAL CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS CARLOS III (F.S.P. CNIO) US Patent					Assay Description The binding assay relies on the LanthaScreen™ Eu-Kinase Binding Assay (Invitrogen). This is a kinase assay platform based on measuring the binding an...				US Patent US10208056 (2019) BindingDB Entry DOI: 10.7270/Q2GB266B
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase haspin (Homo sapiens (Human))	BDBM350198 (US10208056, Compound 30) Show SMILES CC1(C)Oc2cnccc2-c2[nH]c(C(O)=O)c(c12)-c1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C19H17N3O5S/c1-19(2)15-14(10-3-5-11(6-4-10)28(20,25)26)17(18(23)24)22-16(15)12-7-8-21-9-13(12)27-19/h3-9,22H,1-2H3,(H,23,24)(H2,20,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.74E+3	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN DEL SECTOR PÚBLICO ESTATAL CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS CARLOS III (F.S.P. CNIO) US Patent					Assay Description The kinase assay relies on ADP-GloKM biochemical kinase assay (Promega). This is a luminescent kinase assay that measures ADP formed from a kinase re...				US Patent US10208056 (2019) BindingDB Entry DOI: 10.7270/Q2GB266B
					More data for this Ligand-Target Pair