null
SMILES: CC1(C)Oc2cnccc2-c2[nH]c(C(N)=O)c(c12)-c1ccccc1
InChI Key: InChIKey=XHVYRNHFNKLZPA-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cyclin-C/Cyclin-dependent kinase 8 (Homo sapiens (Human)) | BDBM350199 (US10208056, Compound 31) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 29.7 | n/a | n/a | n/a | n/a | n/a | n/a |
FUNDACIÓN DEL SECTOR PÚBLICO ESTATAL CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS CARLOS III (F.S.P. CNIO) US Patent | Assay Description The binding assay relies on the LanthaScreen™ Eu-Kinase Binding Assay (Invitrogen. This is a kinase assay platform based on measuring the binding and... | US Patent US10208056 (2019) BindingDB Entry DOI: 10.7270/Q2GB266B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-C/Cyclin-dependent kinase 19 (Homo sapiens (Human)) | BDBM350199 (US10208056, Compound 31) | PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 107 | n/a | n/a | n/a | n/a | n/a | n/a |
FUNDACIÓN DEL SECTOR PÚBLICO ESTATAL CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS CARLOS III (F.S.P. CNIO) US Patent | Assay Description The binding assay relies on the LanthaScreen™ Eu-Kinase Binding Assay (Invitrogen). This is a kinase assay platform based on measuring the binding an... | US Patent US10208056 (2019) BindingDB Entry DOI: 10.7270/Q2GB266B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase haspin (Homo sapiens (Human)) | BDBM350199 (US10208056, Compound 31) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 73.2 | n/a | n/a | n/a | n/a | n/a | n/a |
FUNDACIÓN DEL SECTOR PÚBLICO ESTATAL CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS CARLOS III (F.S.P. CNIO) US Patent | Assay Description The kinase assay relies on ADP-GloKM biochemical kinase assay (Promega). This is a luminescent kinase assay that measures ADP formed from a kinase re... | US Patent US10208056 (2019) BindingDB Entry DOI: 10.7270/Q2GB266B | |||||||||||
More data for this Ligand-Target Pair |