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SMILES: CCN1CCC2(CC1)Oc1cnccc1-c1[nH]c(cc21)C(N)=O

InChI Key: InChIKey=UHXNWKPYFGCGQC-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 350210   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Serine/threonine-protein kinase haspin


(Homo sapiens (Human))		BDBM350210
PNG
(US10208056, Compound 42)
Show SMILES CCN1CCC2(CC1)Oc1cnccc1-c1[nH]c(cc21)C(N)=O
Show InChI InChI=1S/C17H20N4O2/c1-2-21-7-4-17(5-8-21)12-9-13(16(18)22)20-15(12)11-3-6-19-10-14(11)23-17/h3,6,9-10,20H,2,4-5,7-8H2,1H3,(H2,18,22)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 153n/an/an/an/an/an/a



FUNDACIÓN DEL SECTOR PÚBLICO ESTATAL CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS CARLOS III (F.S.P. CNIO)

US Patent


Assay Description
The kinase assay relies on ADP-GloKM biochemical kinase assay (Promega). This is a luminescent kinase assay that measures ADP formed from a kinase re...

US Patent US10208056 (2019)


BindingDB Entry DOI: 10.7270/Q2GB266B
More data for this
Ligand-Target Pair
Cyclin-C/Cyclin-dependent kinase 8


(Homo sapiens (Human))		BDBM350210
PNG
(US10208056, Compound 42)
Show SMILES CCN1CCC2(CC1)Oc1cnccc1-c1[nH]c(cc21)C(N)=O
Show InChI InChI=1S/C17H20N4O2/c1-2-21-7-4-17(5-8-21)12-9-13(16(18)22)20-15(12)11-3-6-19-10-14(11)23-17/h3,6,9-10,20H,2,4-5,7-8H2,1H3,(H2,18,22)
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 197n/an/an/an/an/an/a



FUNDACIÓN DEL SECTOR PÚBLICO ESTATAL CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS CARLOS III (F.S.P. CNIO)

US Patent


Assay Description
The binding assay relies on the LanthaScreen™ Eu-Kinase Binding Assay (Invitrogen. This is a kinase assay platform based on measuring the binding and...

US Patent US10208056 (2019)


BindingDB Entry DOI: 10.7270/Q2GB266B
More data for this
Ligand-Target Pair