BDBM350213 US10208056, Compound 45

SMILES: COCCn1c(cc2c1-c1ccncc1OC2(C)C)C(N)=O

InChI Key: InChIKey=KVXMBXJEXMWXLQ-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 350213   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
CDK8/Cyclin C (Homo sapiens (Human))	BDBM350213 (US10208056, Compound 45) Show SMILES COCCn1c(cc2c1-c1ccncc1OC2(C)C)C(N)=O Show InChI InChI=1S/C16H19N3O3/c1-16(2)11-8-12(15(17)20)19(6-7-21-3)14(11)10-4-5-18-9-13(10)22-16/h4-5,8-9H,6-7H2,1-3H3,(H2,17,20)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.64	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN DEL SECTOR PÚBLICO ESTATAL CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS CARLOS III (F.S.P. CNIO) US Patent					Assay Description The binding assay relies on the LanthaScreen™ Eu-Kinase Binding Assay (Invitrogen. This is a kinase assay platform based on measuring the binding and...				US Patent US10208056 (2019) BindingDB Entry DOI: 10.7270/Q2GB266B
					More data for this Ligand-Target Pair
CDK19/Cyclin C (Homo sapiens (Human))	BDBM350213 (US10208056, Compound 45) Show SMILES COCCn1c(cc2c1-c1ccncc1OC2(C)C)C(N)=O Show InChI InChI=1S/C16H19N3O3/c1-16(2)11-8-12(15(17)20)19(6-7-21-3)14(11)10-4-5-18-9-13(10)22-16/h4-5,8-9H,6-7H2,1-3H3,(H2,17,20)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11.5	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN DEL SECTOR PÚBLICO ESTATAL CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS CARLOS III (F.S.P. CNIO) US Patent					Assay Description The binding assay relies on the LanthaScreen™ Eu-Kinase Binding Assay (Invitrogen). This is a kinase assay platform based on measuring the binding an...				US Patent US10208056 (2019) BindingDB Entry DOI: 10.7270/Q2GB266B
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase haspin (Homo sapiens (Human))	BDBM350213 (US10208056, Compound 45) Show SMILES COCCn1c(cc2c1-c1ccncc1OC2(C)C)C(N)=O Show InChI InChI=1S/C16H19N3O3/c1-16(2)11-8-12(15(17)20)19(6-7-21-3)14(11)10-4-5-18-9-13(10)22-16/h4-5,8-9H,6-7H2,1-3H3,(H2,17,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	182	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN DEL SECTOR PÚBLICO ESTATAL CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS CARLOS III (F.S.P. CNIO) US Patent					Assay Description The kinase assay relies on ADP-GloKM biochemical kinase assay (Promega). This is a luminescent kinase assay that measures ADP formed from a kinase re...				US Patent US10208056 (2019) BindingDB Entry DOI: 10.7270/Q2GB266B
					More data for this Ligand-Target Pair