BDBM350233 2-(4-(methyl(2-methyl-5-(4- methylpiperazin-1-yl)phenyl)amino) phenoxy)pyrido[3,4-d]pyrimidin-4-ol::US10208039, Example 147

SMILES: CN(c1ccc(Oc2nc(O)c3ccncc3n2)cc1)c1cc(ccc1C)N1CCN(C)CC1

InChI Key: InChIKey=YGFHDCWGLSVOKZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 350233   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM350233 (2-(4-(methyl(2-methyl-5-(4- methylpiperazin-1-yl)p...) Show SMILES CN(c1ccc(Oc2nc(O)c3ccncc3n2)cc1)c1cc(ccc1C)N1CCN(C)CC1 Show InChI InChI=1S/C26H28N6O2/c1-18-4-5-20(32-14-12-30(2)13-15-32)16-24(18)31(3)19-6-8-21(9-7-19)34-26-28-23-17-27-11-10-22(23)25(33)29-26/h4-11,16-17H,12-15H2,1-3H3,(H,28,29,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate-format under the following reaction conditions: 0.3 ...				US Patent US10208039 (2019) BindingDB Entry DOI: 10.7270/Q241706J
					More data for this Ligand-Target Pair