null

SMILES: CN(C)Cc1nc2c3cc(ccc3sc2c(=O)[nH]1)-c1ccc(cc1)C#N

InChI Key: InChIKey=PZACVAVZCMGALO-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 35024   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM35024 (benzothienopyrimidinone deriv., 14i) Show SMILES CN(C)Cc1nc2c3cc(ccc3sc2c(=O)[nH]1)-c1ccc(cc1)C#N Show InChI InChI=1S/C20H16N4OS/c1-24(2)11-17-22-18-15-9-14(13-5-3-12(10-21)4-6-13)7-8-16(15)26-19(18)20(25)23-17/h3-9H,11H2,1-2H3,(H,22,23,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	21	-10.5	n/a	n/a	n/a	n/a	n/a	n/a	25
Abbott Laboratories					Assay Description In 384-well v-bottom polypropylene plates, compound (2% DMSO) was mixed with Pim kinase and peptide substrate, followed by immediate initiation with ...				J Med Chem 52: 6621-36 (2009) Article DOI: 10.1021/jm900943h BindingDB Entry DOI: 10.7270/Q27P8WQW
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM35024 (benzothienopyrimidinone deriv., 14i) Show SMILES CN(C)Cc1nc2c3cc(ccc3sc2c(=O)[nH]1)-c1ccc(cc1)C#N Show InChI InChI=1S/C20H16N4OS/c1-24(2)11-17-22-18-15-9-14(13-5-3-12(10-21)4-6-13)7-8-16(15)26-19(18)20(25)23-17/h3-9H,11H2,1-2H3,(H,22,23,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	5	-11.3	n/a	n/a	n/a	n/a	n/a	n/a	25
Abbott Laboratories					Assay Description In 384-well v-bottom polypropylene plates, compound (2% DMSO) was mixed with Pim kinase and peptide substrate, followed by immediate initiation with ...				J Med Chem 52: 6621-36 (2009) Article DOI: 10.1021/jm900943h BindingDB Entry DOI: 10.7270/Q27P8WQW
					More data for this Ligand-Target Pair