BDBM350253 US10208056, Compound 80

SMILES: CCn1c(cc2c1-c1ccncc1OC21CCCCC1)C(N)=O

InChI Key: InChIKey=FFNTZJOKBZFDQL-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 350253   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
CDK8/Cyclin C (Homo sapiens (Human))	BDBM350253 (US10208056, Compound 80) Show SMILES CCn1c(cc2c1-c1ccncc1OC21CCCCC1)C(N)=O Show InChI InChI=1S/C18H21N3O2/c1-2-21-14(17(19)22)10-13-16(21)12-6-9-20-11-15(12)23-18(13)7-4-3-5-8-18/h6,9-11H,2-5,7-8H2,1H3,(H2,19,22)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.314	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN DEL SECTOR PÚBLICO ESTATAL CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS CARLOS III (F.S.P. CNIO) US Patent					Assay Description The binding assay relies on the LanthaScreen™ Eu-Kinase Binding Assay (Invitrogen. This is a kinase assay platform based on measuring the binding and...				US Patent US10208056 (2019) BindingDB Entry DOI: 10.7270/Q2GB266B
					More data for this Ligand-Target Pair
CDK19/Cyclin C (Homo sapiens (Human))	BDBM350253 (US10208056, Compound 80) Show SMILES CCn1c(cc2c1-c1ccncc1OC21CCCCC1)C(N)=O Show InChI InChI=1S/C18H21N3O2/c1-2-21-14(17(19)22)10-13-16(21)12-6-9-20-11-15(12)23-18(13)7-4-3-5-8-18/h6,9-11H,2-5,7-8H2,1H3,(H2,19,22)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.770	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN DEL SECTOR PÚBLICO ESTATAL CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS CARLOS III (F.S.P. CNIO) US Patent					Assay Description The binding assay relies on the LanthaScreen™ Eu-Kinase Binding Assay (Invitrogen). This is a kinase assay platform based on measuring the binding an...				US Patent US10208056 (2019) BindingDB Entry DOI: 10.7270/Q2GB266B
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase haspin (Homo sapiens (Human))	BDBM350253 (US10208056, Compound 80) Show SMILES CCn1c(cc2c1-c1ccncc1OC21CCCCC1)C(N)=O Show InChI InChI=1S/C18H21N3O2/c1-2-21-14(17(19)22)10-13-16(21)12-6-9-20-11-15(12)23-18(13)7-4-3-5-8-18/h6,9-11H,2-5,7-8H2,1H3,(H2,19,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.56	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN DEL SECTOR PÚBLICO ESTATAL CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS CARLOS III (F.S.P. CNIO) US Patent					Assay Description The kinase assay relies on ADP-GloKM biochemical kinase assay (Promega). This is a luminescent kinase assay that measures ADP formed from a kinase re...				US Patent US10208056 (2019) BindingDB Entry DOI: 10.7270/Q2GB266B
					More data for this Ligand-Target Pair