BDBM350256 US10208056, Compound 83
SMILES: Cn1c(cc2c1-c1ccncc1OC21CCCCC1)C(N)=O
InChI Key: InChIKey=QXPHUXPNTWFKOR-UHFFFAOYSA-N
Data: 3 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
CDK8/Cyclin C (Homo sapiens (Human)) | BDBM350256 (US10208056, Compound 83) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.278 | n/a | n/a | n/a | n/a | n/a | n/a |
FUNDACIÓN DEL SECTOR PÚBLICO ESTATAL CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS CARLOS III (F.S.P. CNIO) US Patent | Assay Description The binding assay relies on the LanthaScreen™ Eu-Kinase Binding Assay (Invitrogen. This is a kinase assay platform based on measuring the binding and... | US Patent US10208056 (2019) BindingDB Entry DOI: 10.7270/Q2GB266B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CDK19/Cyclin C (Homo sapiens (Human)) | BDBM350256 (US10208056, Compound 83) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.41 | n/a | n/a | n/a | n/a | n/a | n/a |
FUNDACIÓN DEL SECTOR PÚBLICO ESTATAL CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS CARLOS III (F.S.P. CNIO) US Patent | Assay Description The binding assay relies on the LanthaScreen™ Eu-Kinase Binding Assay (Invitrogen). This is a kinase assay platform based on measuring the binding an... | US Patent US10208056 (2019) BindingDB Entry DOI: 10.7270/Q2GB266B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase haspin (Homo sapiens (Human)) | BDBM350256 (US10208056, Compound 83) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 9.80 | n/a | n/a | n/a | n/a | n/a | n/a |
FUNDACIÓN DEL SECTOR PÚBLICO ESTATAL CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS CARLOS III (F.S.P. CNIO) US Patent | Assay Description The kinase assay relies on ADP-GloKM biochemical kinase assay (Promega). This is a luminescent kinase assay that measures ADP formed from a kinase re... | US Patent US10208056 (2019) BindingDB Entry DOI: 10.7270/Q2GB266B | |||||||||||
More data for this Ligand-Target Pair |