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SMILES: CCn1c(C(N)=O)c(c2c1-c1ccncc1OC2(C)C)-c1cccc(OC)c1

InChI Key: InChIKey=YENIGUGPROEFFL-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 350261   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Serine/threonine-protein kinase haspin


(Homo sapiens (Human))		BDBM350261
PNG
(US10208056, Compound 88)
Show SMILES CCn1c(C(N)=O)c(c2c1-c1ccncc1OC2(C)C)-c1cccc(OC)c1
Show InChI InChI=1S/C22H23N3O3/c1-5-25-19-15-9-10-24-12-16(15)28-22(2,3)18(19)17(20(25)21(23)26)13-7-6-8-14(11-13)27-4/h6-12H,5H2,1-4H3,(H2,23,26)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 106n/an/an/an/an/an/a



FUNDACIÓN DEL SECTOR PÚBLICO ESTATAL CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS CARLOS III (F.S.P. CNIO)

US Patent


Assay Description
The kinase assay relies on ADP-GloKM biochemical kinase assay (Promega). This is a luminescent kinase assay that measures ADP formed from a kinase re...

US Patent US10208056 (2019)


BindingDB Entry DOI: 10.7270/Q2GB266B
More data for this
Ligand-Target Pair
Cyclin-C/Cyclin-dependent kinase 8


(Homo sapiens (Human))		BDBM350261
PNG
(US10208056, Compound 88)
Show SMILES CCn1c(C(N)=O)c(c2c1-c1ccncc1OC2(C)C)-c1cccc(OC)c1
Show InChI InChI=1S/C22H23N3O3/c1-5-25-19-15-9-10-24-12-16(15)28-22(2,3)18(19)17(20(25)21(23)26)13-7-6-8-14(11-13)27-4/h6-12H,5H2,1-4H3,(H2,23,26)
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 13.9n/an/an/an/an/an/a



FUNDACIÓN DEL SECTOR PÚBLICO ESTATAL CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS CARLOS III (F.S.P. CNIO)

US Patent


Assay Description
The binding assay relies on the LanthaScreen™ Eu-Kinase Binding Assay (Invitrogen. This is a kinase assay platform based on measuring the binding and...

US Patent US10208056 (2019)


BindingDB Entry DOI: 10.7270/Q2GB266B
More data for this
Ligand-Target Pair