BDBM350270 US10208056, Compound 105

SMILES: CCn1c(C(N)=O)c(Cl)c2c1-c1ccncc1OC21CCCCC1

InChI Key: InChIKey=ONHQIVOXCQMDSF-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 350270   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase haspin (Homo sapiens (Human))	BDBM350270 (US10208056, Compound 105) Show SMILES CCn1c(C(N)=O)c(Cl)c2c1-c1ccncc1OC21CCCCC1 Show InChI InChI=1S/C18H20ClN3O2/c1-2-22-15-11-6-9-21-10-12(11)24-18(7-4-3-5-8-18)13(15)14(19)16(22)17(20)23/h6,9-10H,2-5,7-8H2,1H3,(H2,20,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8.82	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN DEL SECTOR PÚBLICO ESTATAL CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS CARLOS III (F.S.P. CNIO) US Patent					Assay Description The kinase assay relies on ADP-GloKM biochemical kinase assay (Promega). This is a luminescent kinase assay that measures ADP formed from a kinase re...				US Patent US10208056 (2019) BindingDB Entry DOI: 10.7270/Q2GB266B
					More data for this Ligand-Target Pair
CDK8/Cyclin C (Homo sapiens (Human))	BDBM350270 (US10208056, Compound 105) Show SMILES CCn1c(C(N)=O)c(Cl)c2c1-c1ccncc1OC21CCCCC1 Show InChI InChI=1S/C18H20ClN3O2/c1-2-22-15-11-6-9-21-10-12(11)24-18(7-4-3-5-8-18)13(15)14(19)16(22)17(20)23/h6,9-10H,2-5,7-8H2,1H3,(H2,20,23)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.41	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN DEL SECTOR PÚBLICO ESTATAL CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS CARLOS III (F.S.P. CNIO) US Patent					Assay Description The binding assay relies on the LanthaScreen™ Eu-Kinase Binding Assay (Invitrogen. This is a kinase assay platform based on measuring the binding and...				US Patent US10208056 (2019) BindingDB Entry DOI: 10.7270/Q2GB266B
					More data for this Ligand-Target Pair