BDBM350359 US9802904, 10

SMILES: FC(F)(F)c1ccccc1-c1ncc2c(NCc3ccc(Cl)cc3)cccc2n1

InChI Key: InChIKey=HOOXGGNIWQLPCO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 350359   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
USP1/UAF1 (Homo sapiens (Human))	BDBM350359 (US9802904, 10) Show SMILES FC(F)(F)c1ccccc1-c1ncc2c(NCc3ccc(Cl)cc3)cccc2n1 Show InChI InChI=1S/C22H15ClF3N3/c23-15-10-8-14(9-11-15)12-27-19-6-3-7-20-17(19)13-28-21(29-20)16-4-1-2-5-18(16)22(24,25)26/h1-11,13,27H,12H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The United States of America, as represented by the Secretary, Department of Health and Human Services; University of Delaware US Patent					Assay Description This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...				US Patent US9802904 (2017) BindingDB Entry DOI: 10.7270/Q2TF00H8
					More data for this Ligand-Target Pair