BDBM350367 US9802904, 18

SMILES: FC(F)(F)c1ccccc1-c1ncc2c(NCc3ccc(cc3)-c3cccc(Cl)c3)cccc2n1

InChI Key: InChIKey=RQWDZMAEUJLKSF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 350367   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
USP1/UAF1 (Homo sapiens (Human))	BDBM350367 (US9802904, 18) Show SMILES FC(F)(F)c1ccccc1-c1ncc2c(NCc3ccc(cc3)-c3cccc(Cl)c3)cccc2n1 Show InChI InChI=1S/C28H19ClF3N3/c29-21-6-3-5-20(15-21)19-13-11-18(12-14-19)16-33-25-9-4-10-26-23(25)17-34-27(35-26)22-7-1-2-8-24(22)28(30,31)32/h1-15,17,33H,16H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
The United States of America, as represented by the Secretary, Department of Health and Human Services; University of Delaware US Patent					Assay Description This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...				US Patent US9802904 (2017) BindingDB Entry DOI: 10.7270/Q2TF00H8
					More data for this Ligand-Target Pair