BDBM350368 US9802904, 19

SMILES: FC(F)(F)c1ccccc1-c1ncc2c(NCc3ccc(cc3)-c3ccncc3)cccc2n1

InChI Key: InChIKey=LMWHTNFQWCVVHK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 350368   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
USP1/UAF1 (Homo sapiens (Human))	BDBM350368 (US9802904, 19) Show SMILES FC(F)(F)c1ccccc1-c1ncc2c(NCc3ccc(cc3)-c3ccncc3)cccc2n1 Show InChI InChI=1S/C27H19F3N4/c28-27(29,30)23-5-2-1-4-21(23)26-33-17-22-24(6-3-7-25(22)34-26)32-16-18-8-10-19(11-9-18)20-12-14-31-15-13-20/h1-15,17,32H,16H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	480	n/a	n/a	n/a	n/a	n/a	n/a
The United States of America, as represented by the Secretary, Department of Health and Human Services; University of Delaware US Patent					Assay Description This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...				US Patent US9802904 (2017) BindingDB Entry DOI: 10.7270/Q2TF00H8
					More data for this Ligand-Target Pair