BDBM350369 US9802904, 20::US9802904, 21
SMILES: FC(F)(F)c1ccccc1-c1ncc2c(NCc3ccc(cc3)-c3cccnc3)cccc2n1
InChI Key: InChIKey=QJJJRIWFUUHVOE-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
USP1/UAF1 (Homo sapiens (Human)) | BDBM350369 (US9802904, 20 | US9802904, 21) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The United States of America, as represented by the Secretary, Department of Health and Human Services; University of Delaware US Patent | Assay Description This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ... | US Patent US9802904 (2017) BindingDB Entry DOI: 10.7270/Q2TF00H8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
USP1/UAF1 (Homo sapiens (Human)) | BDBM350369 (US9802904, 20 | US9802904, 21) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 610 | n/a | n/a | n/a | n/a | n/a | n/a |
The United States of America, as represented by the Secretary, Department of Health and Human Services; University of Delaware US Patent | Assay Description This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ... | US Patent US9802904 (2017) BindingDB Entry DOI: 10.7270/Q2TF00H8 | |||||||||||
More data for this Ligand-Target Pair |