BDBM350376 US9802904, 50

SMILES: CC(C)c1ccccc1-c1nc(NCc2ccc(cc2)-c2ccccc2)c2sccc2n1

InChI Key: InChIKey=WOXKWXOOAZXVAJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 350376   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
USP1/UAF1 (Homo sapiens (Human))	BDBM350376 (US9802904, 50) Show SMILES CC(C)c1ccccc1-c1nc(NCc2ccc(cc2)-c2ccccc2)c2sccc2n1 Show InChI InChI=1S/C28H25N3S/c1-19(2)23-10-6-7-11-24(23)27-30-25-16-17-32-26(25)28(31-27)29-18-20-12-14-22(15-13-20)21-8-4-3-5-9-21/h3-17,19H,18H2,1-2H3,(H,29,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
The United States of America, as represented by the Secretary, Department of Health and Human Services; University of Delaware US Patent					Assay Description This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...				US Patent US9802904 (2017) BindingDB Entry DOI: 10.7270/Q2TF00H8
					More data for this Ligand-Target Pair