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SMILES: CC(C)c1ccccc1-c1nc(NCc2ccc(cc2)-c2ccccc2)c2ccsc2n1

InChI Key: InChIKey=OHRMASGYMKXPKD-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 350377   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Ubiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48


(Homo sapiens (Human))		BDBM350377
PNG
(US9802904, 51)
Show SMILES CC(C)c1ccccc1-c1nc(NCc2ccc(cc2)-c2ccccc2)c2ccsc2n1
Show InChI InChI=1S/C28H25N3S/c1-19(2)23-10-6-7-11-24(23)27-30-26(25-16-17-32-28(25)31-27)29-18-20-12-14-22(15-13-20)21-8-4-3-5-9-21/h3-17,19H,18H2,1-2H3,(H,29,30,31)
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US Patent
n/an/a 120n/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services; University of Delaware

US Patent


Assay Description
This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...

US Patent US9802904 (2017)


BindingDB Entry DOI: 10.7270/Q2TF00H8
More data for this
Ligand-Target Pair