BDBM350381 US9802904, 55

SMILES: CC(C)c1ccccc1C1=NC2CNCCC2C(NCc2ccc(cc2)-c2ccccc2)=N1

InChI Key: InChIKey=YGRXUVSUQCVWBR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 350381   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ubiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48 (Homo sapiens (Human))	BDBM350381 (US9802904, 55) Show SMILES CC(C)c1ccccc1C1=NC2CNCCC2C(NCc2ccc(cc2)-c2ccccc2)=N1 |c:35,t:10| Show InChI InChI=1S/C29H32N4/c1-20(2)24-10-6-7-11-25(24)29-32-27-19-30-17-16-26(27)28(33-29)31-18-21-12-14-23(15-13-21)22-8-4-3-5-9-22/h3-15,20,26-27,30H,16-19H2,1-2H3,(H,31,32,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
The United States of America, as represented by the Secretary, Department of Health and Human Services; University of Delaware US Patent					Assay Description This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...				US Patent US9802904 (2017) BindingDB Entry DOI: 10.7270/Q2TF00H8
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