BDBM35045 benzothienopyrimidinone deriv., 19c

SMILES: Oc1cccc(NCc2nc3c4cc(ccc4sc3c(=O)[nH]2)-c2ccccc2)c1

InChI Key: InChIKey=FMYNFWDKPWRVHK-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 35045   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM35045 (benzothienopyrimidinone deriv., 19c) Show SMILES Oc1cccc(NCc2nc3c4cc(ccc4sc3c(=O)[nH]2)-c2ccccc2)c1 Show InChI InChI=1S/C23H17N3O2S/c27-17-8-4-7-16(12-17)24-13-20-25-21-18-11-15(14-5-2-1-3-6-14)9-10-19(18)29-22(21)23(28)26-20/h1-12,24,27H,13H2,(H,25,26,28)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	2	-11.9	n/a	n/a	n/a	n/a	n/a	n/a	25
Abbott Laboratories					Assay Description In 384-well v-bottom polypropylene plates, compound (2% DMSO) was mixed with Pim kinase and peptide substrate, followed by immediate initiation with ...				J Med Chem 52: 6621-36 (2009) Article DOI: 10.1021/jm900943h BindingDB Entry DOI: 10.7270/Q27P8WQW
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM35045 (benzothienopyrimidinone deriv., 19c) Show SMILES Oc1cccc(NCc2nc3c4cc(ccc4sc3c(=O)[nH]2)-c2ccccc2)c1 Show InChI InChI=1S/C23H17N3O2S/c27-17-8-4-7-16(12-17)24-13-20-25-21-18-11-15(14-5-2-1-3-6-14)9-10-19(18)29-22(21)23(28)26-20/h1-12,24,27H,13H2,(H,25,26,28)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	939	-8.22	n/a	n/a	n/a	n/a	n/a	n/a	25
Abbott Laboratories					Assay Description In 384-well v-bottom polypropylene plates, compound (2% DMSO) was mixed with Pim kinase and peptide substrate, followed by immediate initiation with ...				J Med Chem 52: 6621-36 (2009) Article DOI: 10.1021/jm900943h BindingDB Entry DOI: 10.7270/Q27P8WQW
					More data for this Ligand-Target Pair