BDBM351869 US9796716, Compound 114

SMILES: Cc1ncc(COc2cc(F)cc(Oc3ccc(cc3)-c3nn(CCCO)c4ncnc(N)c34)c2)cn1

InChI Key: InChIKey=SLSGFEUVNQSRRR-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 351869   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM351869 (US9796716, Compound 114) Show SMILES Cc1ncc(COc2cc(F)cc(Oc3ccc(cc3)-c3nn(CCCO)c4ncnc(N)c34)c2)cn1 Show InChI InChI=1S/C26H24FN7O3/c1-16-29-12-17(13-30-16)14-36-21-9-19(27)10-22(11-21)37-20-5-3-18(4-6-20)24-23-25(28)31-15-32-26(23)34(33-24)7-2-8-35/h3-6,9-13,15,35H,2,7-8,14H2,1H3,(H2,28,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
PHARMASCIENCE, INC. US Patent					Assay Description Fluorescence polarization-based kinase assays were performed in 384 well-plate format using histidine tagged recombinant human full-length Bruton Aga...				US Patent US9796716 (2017) BindingDB Entry DOI: 10.7270/Q2MW2K8J
					More data for this Ligand-Target Pair