BDBM351922 US9802904, 64

SMILES: CSc1cnc(nc1NCc1ccc(cc1)-c1ccccc1)-c1ccccc1C(C)C

InChI Key: InChIKey=VSEXWFQETXEBSQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 351922   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ubiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48 (Homo sapiens (Human))	BDBM351922 (US9802904, 64) Show SMILES CSc1cnc(nc1NCc1ccc(cc1)-c1ccccc1)-c1ccccc1C(C)C Show InChI InChI=1S/C27H27N3S/c1-19(2)23-11-7-8-12-24(23)26-29-18-25(31-3)27(30-26)28-17-20-13-15-22(16-14-20)21-9-5-4-6-10-21/h4-16,18-19H,17H2,1-3H3,(H,28,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	86	n/a	n/a	n/a	n/a	n/a	n/a
The United States of America, as represented by the Secretary, Department of Health and Human Services; University of Delaware US Patent					Assay Description This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...				US Patent US9802904 (2017) BindingDB Entry DOI: 10.7270/Q2TF00H8
					More data for this Ligand-Target Pair