BDBM351932 US9802904, 65

SMILES: CC(C)c1ccccc1-c1nc(C)cc(NCc2ccc(cc2)-c2ccccc2)n1

InChI Key: InChIKey=AJZRKPXCOQSJMY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 351932   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
USP1/UAF1 (Homo sapiens (Human))	BDBM351932 (US9802904, 65) Show SMILES CC(C)c1ccccc1-c1nc(C)cc(NCc2ccc(cc2)-c2ccccc2)n1 Show InChI InChI=1S/C27H27N3/c1-19(2)24-11-7-8-12-25(24)27-29-20(3)17-26(30-27)28-18-21-13-15-23(16-14-21)22-9-5-4-6-10-22/h4-17,19H,18H2,1-3H3,(H,28,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	480	n/a	n/a	n/a	n/a	n/a	n/a
The United States of America, as represented by the Secretary, Department of Health and Human Services; University of Delaware US Patent					Assay Description This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...				US Patent US9802904 (2017) BindingDB Entry DOI: 10.7270/Q2TF00H8
					More data for this Ligand-Target Pair