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SMILES: CC(C)c1ccccc1-c1ncc(C)c(NCc2ccc(cc2)-c2cc[nH]n2)n1

InChI Key: InChIKey=RFUYFRZYMMYGEE-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 352027   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Ubiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48


(Homo sapiens (Human))		BDBM352027
PNG
(US9802904, 88)
Show SMILES CC(C)c1ccccc1-c1ncc(C)c(NCc2ccc(cc2)-c2cc[nH]n2)n1
Show InChI InChI=1S/C24H25N5/c1-16(2)20-6-4-5-7-21(20)24-25-14-17(3)23(28-24)26-15-18-8-10-19(11-9-18)22-12-13-27-29-22/h4-14,16H,15H2,1-3H3,(H,27,29)(H,25,26,28)
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US Patent
n/an/a 150n/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services; University of Delaware

US Patent


Assay Description
This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...

US Patent US9802904 (2017)


BindingDB Entry DOI: 10.7270/Q2TF00H8
More data for this
Ligand-Target Pair