BDBM352480 US9809545, 6Aa

SMILES: Fc1ccc(CC(c2nnc(o2)-c2cccnc2)n2ccc(cc2=O)-c2cc(Cl)ccc2-n2cnnn2)cc1

InChI Key: InChIKey=LAHHVIQTDQKRFL-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 352480   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor IX (Homo sapiens (Human))	BDBM352480 (US9809545, 6Aa) Show SMILES Fc1ccc(CC(c2nnc(o2)-c2cccnc2)n2ccc(cc2=O)-c2cc(Cl)ccc2-n2cnnn2)cc1 Show InChI InChI=1S/C27H18ClFN8O2/c28-20-5-8-23(37-16-31-34-35-37)22(14-20)18-9-11-36(25(38)13-18)24(12-17-3-6-21(29)7-4-17)27-33-32-26(39-27)19-2-1-10-30-15-19/h1-11,13-16,24H,12H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	280	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 150 mM NaCl, 5 mM CaCl2, and 0.1% PEG 8000 (polyethylene glycol; JT Ba...				US Patent US9809545 (2017) BindingDB Entry DOI: 10.7270/Q24Q7X4Q
					More data for this Ligand-Target Pair