BDBM35252 3-(phenylsulfonyl)-1H-indole, 33b
SMILES: CC(C)NCCCc1cccc2[nH]cc(c12)S(=O)(=O)c1ccccc1
InChI Key: InChIKey=YHPHFVMVXIQRCD-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Sodium-dependent noradrenaline transporter (Homo sapiens (Human)) | BDBM35252 (3-(phenylsulfonyl)-1H-indole, 33b) | Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | 13 | -11.2 | 12 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Wyeth Research | Assay Description Compounds were evaluated the inhibition of [3H] nisoxetine binding to MDCK-Net6 cells, stably transfected with the human norepinephrine transporter (... | Bioorg Med Chem 17: 7802-15 (2009) Article DOI: 10.1016/j.bmc.2009.09.023 BindingDB Entry DOI: 10.7270/Q26Q1VK2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Homo sapiens (Human)) | BDBM35252 (3-(phenylsulfonyl)-1H-indole, 33b) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | 619 | n/a | 5.98E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research | Assay Description Compounds were evaluated the inhibition of [3H] ketanserin binding to membranes from CHO cells, stably transfected with the human 5-HT2A receptor. Da... | Bioorg Med Chem 17: 7802-15 (2009) Article DOI: 10.1016/j.bmc.2009.09.023 BindingDB Entry DOI: 10.7270/Q26Q1VK2 | |||||||||||
More data for this Ligand-Target Pair |