BDBM35414 5-oxidanylidene-N3-(oxolan-2-ylmethyl)-N8-pentyl-1-sulfanylidene-4H-[1,3]thiazolo[3,4-a]quinazoline-3,8-dicarboxamide::5-oxo-3-N-(oxolan-2-ylmethyl)-8-N-pentyl-1-sulfanylidene-4H-[1,3]thiazolo[3,4-a]quinazoline-3,8-dicarboxamide::5-oxo-N3-(2-oxolanylmethyl)-N8-pentyl-1-sulfanylidene-4H-thiazolo[3,4-a]quinazoline-3,8-dicarboxamide::5-oxo-N~8~-pentyl-N~3~-(tetrahydrofuran-2-ylmethyl)-1-thioxo-4,5-dihydro[1,3]thiazolo[3,4-a]quinazoline-3,8-dicarboxamide::MLS000094742::N'-amyl-5-keto-N-(tetrahydrofurfuryl)-1-thioxo-4H-thiazolo[3,4-a]quinazoline-3,8-dicarboxamide::SMR000030295::cid_3245487

SMILES: CCCCCNC(=O)c1ccc2c(c1)n1c([nH]c2=O)c(sc1=S)C(=O)NCC1CCCO1

InChI Key: InChIKey=SMIYUZPFDZKHFF-UHFFFAOYSA-N

Data: 2 KI  11 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 35414   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
fMet-Leu-Phe receptor (Homo sapiens (Human))	BDBM35414 (5-oxidanylidene-N3-(oxolan-2-ylmethyl)-N8-pentyl-1...) Show SMILES CCCCCNC(=O)c1ccc2c(c1)n1c([nH]c2=O)c(sc1=S)C(=O)NCC1CCCO1 Show InChI InChI=1S/C22H26N4O4S2/c1-2-3-4-9-23-19(27)13-7-8-15-16(11-13)26-18(25-20(15)28)17(32-22(26)31)21(29)24-12-14-6-5-10-30-14/h7-8,11,14H,2-6,9-10,12H2,1H3,(H,23,27)(H,24,29)(H,25,28)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	2.66E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph...				PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2NZ862K
					More data for this Ligand-Target Pair
N-formyl peptide receptor 2 (Homo sapiens (Human))	BDBM35414 (5-oxidanylidene-N3-(oxolan-2-ylmethyl)-N8-pentyl-1...) Show SMILES CCCCCNC(=O)c1ccc2c(c1)n1c([nH]c2=O)c(sc1=S)C(=O)NCC1CCCO1 Show InChI InChI=1S/C22H26N4O4S2/c1-2-3-4-9-23-19(27)13-7-8-15-16(11-13)26-18(25-20(15)28)17(32-22(26)31)21(29)24-12-14-6-5-10-30-14/h7-8,11,14H,2-6,9-10,12H2,1H3,(H,23,27)(H,24,29)(H,25,28)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	>4.03E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph....				PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2DF6PMF
					More data for this Ligand-Target Pair
fMet-Leu-Phe receptor (Homo sapiens (Human))	BDBM35414 (5-oxidanylidene-N3-(oxolan-2-ylmethyl)-N8-pentyl-1...) Show SMILES CCCCCNC(=O)c1ccc2c(c1)n1c([nH]c2=O)c(sc1=S)C(=O)NCC1CCCO1 Show InChI InChI=1S/C22H26N4O4S2/c1-2-3-4-9-23-19(27)13-7-8-15-16(11-13)26-18(25-20(15)28)17(32-22(26)31)21(29)24-12-14-6-5-10-30-14/h7-8,11,14H,2-6,9-10,12H2,1H3,(H,23,27)(H,24,29)(H,25,28)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	4.07E+4	n/a	n/a	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph...				PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2J67FB5
					More data for this Ligand-Target Pair
Dual Specificity Protein Phosphatase 1 (Homo sapiens (Human))	BDBM35414 (5-oxidanylidene-N3-(oxolan-2-ylmethyl)-N8-pentyl-1...) Show SMILES CCCCCNC(=O)c1ccc2c(c1)n1c([nH]c2=O)c(sc1=S)C(=O)NCC1CCCO1 Show InChI InChI=1S/C22H26N4O4S2/c1-2-3-4-9-23-19(27)13-7-8-15-16(11-13)26-18(25-20(15)28)17(32-22(26)31)21(29)24-12-14-6-5-10-30-14/h7-8,11,14H,2-6,9-10,12H2,1H3,(H,23,27)(H,24,29)(H,25,28)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	3.67E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Molecular Library Screening Center Curated by PubChem BioAssay					Assay Description The MKP-1 dose response Active/Probe assessment-Catalase assay has been developed to evaluate the effects of adding 100 U/mL of Catalase on the MKP-1...				PubChem Bioassay (2006) BindingDB Entry DOI: 10.7270/Q2VH5M71
					More data for this Ligand-Target Pair
Dual Specificity Protein Phosphatase 1 (Homo sapiens (Human))	BDBM35414 (5-oxidanylidene-N3-(oxolan-2-ylmethyl)-N8-pentyl-1...) Show SMILES CCCCCNC(=O)c1ccc2c(c1)n1c([nH]c2=O)c(sc1=S)C(=O)NCC1CCCO1 Show InChI InChI=1S/C22H26N4O4S2/c1-2-3-4-9-23-19(27)13-7-8-15-16(11-13)26-18(25-20(15)28)17(32-22(26)31)21(29)24-12-14-6-5-10-30-14/h7-8,11,14H,2-6,9-10,12H2,1H3,(H,23,27)(H,24,29)(H,25,28)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	3.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Molecular Library Screening Center Curated by PubChem BioAssay					Assay Description The MKP-1 dose response assay Active/Probe Assessment Assay - Reproducibility testing has been developed to test the reproducibility of MKP-1 inhibit...				PubChem Bioassay (2006) BindingDB Entry DOI: 10.7270/Q2QR4VH9
					More data for this Ligand-Target Pair
MKP-3 (Rattus norvegicus)	BDBM35414 (5-oxidanylidene-N3-(oxolan-2-ylmethyl)-N8-pentyl-1...) Show SMILES CCCCCNC(=O)c1ccc2c(c1)n1c([nH]c2=O)c(sc1=S)C(=O)NCC1CCCO1 Show InChI InChI=1S/C22H26N4O4S2/c1-2-3-4-9-23-19(27)13-7-8-15-16(11-13)26-18(25-20(15)28)17(32-22(26)31)21(29)24-12-14-6-5-10-30-14/h7-8,11,14H,2-6,9-10,12H2,1H3,(H,23,27)(H,24,29)(H,25,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Molecular Library Screening Center Curated by PubChem BioAssay					Assay Description The in vitro MKP-3 Phosphatase dose response hit/probe assessment assay has been developed and run at the University of Pittsburgh Molecular Screenin...				PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2H70D6B
					More data for this Ligand-Target Pair
MKP-3 (Rattus norvegicus)	BDBM35414 (5-oxidanylidene-N3-(oxolan-2-ylmethyl)-N8-pentyl-1...) Show SMILES CCCCCNC(=O)c1ccc2c(c1)n1c([nH]c2=O)c(sc1=S)C(=O)NCC1CCCO1 Show InChI InChI=1S/C22H26N4O4S2/c1-2-3-4-9-23-19(27)13-7-8-15-16(11-13)26-18(25-20(15)28)17(32-22(26)31)21(29)24-12-14-6-5-10-30-14/h7-8,11,14H,2-6,9-10,12H2,1H3,(H,23,27)(H,24,29)(H,25,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Molecular Library Screening Center Curated by PubChem BioAssay					Assay Description The MKP-3 dose response Active/Probe assessment-Catalase assay has been developed to evaluate the effects of adding 100 U/mL of Catalase on the MKP-3...				PubChem Bioassay (2006) BindingDB Entry DOI: 10.7270/Q2M043S8
					More data for this Ligand-Target Pair
MKP-3 (Rattus norvegicus)	BDBM35414 (5-oxidanylidene-N3-(oxolan-2-ylmethyl)-N8-pentyl-1...) Show SMILES CCCCCNC(=O)c1ccc2c(c1)n1c([nH]c2=O)c(sc1=S)C(=O)NCC1CCCO1 Show InChI InChI=1S/C22H26N4O4S2/c1-2-3-4-9-23-19(27)13-7-8-15-16(11-13)26-18(25-20(15)28)17(32-22(26)31)21(29)24-12-14-6-5-10-30-14/h7-8,11,14H,2-6,9-10,12H2,1H3,(H,23,27)(H,24,29)(H,25,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Molecular Library Screening Center Curated by PubChem BioAssay					Assay Description The MKP-3 dose response assay Active/Probe Assessment Assay - Reproducibility testing has been developed to test the reproducibility of MKP-3 inhibit...				PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2G73C2Z
					More data for this Ligand-Target Pair
Dual specificity phosphatase Cdc25B (Homo sapiens (Human))	BDBM35414 (5-oxidanylidene-N3-(oxolan-2-ylmethyl)-N8-pentyl-1...) Show SMILES CCCCCNC(=O)c1ccc2c(c1)n1c([nH]c2=O)c(sc1=S)C(=O)NCC1CCCO1 Show InChI InChI=1S/C22H26N4O4S2/c1-2-3-4-9-23-19(27)13-7-8-15-16(11-13)26-18(25-20(15)28)17(32-22(26)31)21(29)24-12-14-6-5-10-30-14/h7-8,11,14H,2-6,9-10,12H2,1H3,(H,23,27)(H,24,29)(H,25,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Molecular Library Screening Center Curated by PubChem BioAssay					Assay Description The MKP-1 Dual Specificity Protein Tyrosine Phosphatase Probe Assessment Cdc25B Dose Response Selectivity Assay has been developed to evaluate the PT...				PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2125R2H
					More data for this Ligand-Target Pair
Zinc aminopeptidase (Plasmodium falciparum (isolate FcB1 / Columbia))	BDBM35414 (5-oxidanylidene-N3-(oxolan-2-ylmethyl)-N8-pentyl-1...) Show SMILES CCCCCNC(=O)c1ccc2c(c1)n1c([nH]c2=O)c(sc1=S)C(=O)NCC1CCCO1 Show InChI InChI=1S/C22H26N4O4S2/c1-2-3-4-9-23-19(27)13-7-8-15-16(11-13)26-18(25-20(15)28)17(32-22(26)31)21(29)24-12-14-6-5-10-30-14/h7-8,11,14H,2-6,9-10,12H2,1H3,(H,23,27)(H,24,29)(H,25,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	3.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
SRMLSC Curated by PubChem BioAssay					Assay Description Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q27H1H0J
					More data for this Ligand-Target Pair
streptokinase A precursor (Streptococcus pyogenes M1 GAS)	BDBM35414 (5-oxidanylidene-N3-(oxolan-2-ylmethyl)-N8-pentyl-1...) Show SMILES CCCCCNC(=O)c1ccc2c(c1)n1c([nH]c2=O)c(sc1=S)C(=O)NCC1CCCO1 Show InChI InChI=1S/C22H26N4O4S2/c1-2-3-4-9-23-19(27)13-7-8-15-16(11-13)26-18(25-20(15)28)17(32-22(26)31)21(29)24-12-14-6-5-10-30-14/h7-8,11,14H,2-6,9-10,12H2,1H3,(H,23,27)(H,24,29)(H,25,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	2.11E+4	n/a	n/a	n/a	n/a
Broad Institute Curated by PubChem BioAssay					Assay Description Keywords: Group A streptococcus, GAS, streptokinase, expression, virulence, inhibition, dose response, EC50 Assay Overview: The goal of this assa...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2736PBV
					More data for this Ligand-Target Pair
Dual Specificity Protein Phosphatase 1 (Homo sapiens (Human))	BDBM35414 (5-oxidanylidene-N3-(oxolan-2-ylmethyl)-N8-pentyl-1...) Show SMILES CCCCCNC(=O)c1ccc2c(c1)n1c([nH]c2=O)c(sc1=S)C(=O)NCC1CCCO1 Show InChI InChI=1S/C22H26N4O4S2/c1-2-3-4-9-23-19(27)13-7-8-15-16(11-13)26-18(25-20(15)28)17(32-22(26)31)21(29)24-12-14-6-5-10-30-14/h7-8,11,14H,2-6,9-10,12H2,1H3,(H,23,27)(H,24,29)(H,25,28)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	3.67E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Molecular Library Screening Center Curated by PubChem BioAssay					Assay Description The MKP-1 dose response Active/Probe assessment-DTT assay has been developed to evaluate the effects of increased DTT concentration on the MKP-1 inhi...				PubChem Bioassay (2006) BindingDB Entry DOI: 10.7270/Q20863PV
					More data for this Ligand-Target Pair
Dual Specificity Protein Phosphatase 1 (Homo sapiens (Human))	BDBM35414 (5-oxidanylidene-N3-(oxolan-2-ylmethyl)-N8-pentyl-1...) Show SMILES CCCCCNC(=O)c1ccc2c(c1)n1c([nH]c2=O)c(sc1=S)C(=O)NCC1CCCO1 Show InChI InChI=1S/C22H26N4O4S2/c1-2-3-4-9-23-19(27)13-7-8-15-16(11-13)26-18(25-20(15)28)17(32-22(26)31)21(29)24-12-14-6-5-10-30-14/h7-8,11,14H,2-6,9-10,12H2,1H3,(H,23,27)(H,24,29)(H,25,28)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	3.84E+4	n/a	n/a	n/a	n/a	7.0	22
University of Pittsburgh Molecular Library Screening Center Curated by PubChem BioAssay					Assay Description The MKP-1 HTS confirmation dose response assay has been developed to confirm actives identified in the MH-76391 In vitro HTS assay for MKP-1 inhibito...				PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2F769WQ
					More data for this Ligand-Target Pair
N-formyl peptide receptor 2 (Homo sapiens (Human))	BDBM35414 (5-oxidanylidene-N3-(oxolan-2-ylmethyl)-N8-pentyl-1...) Show SMILES CCCCCNC(=O)c1ccc2c(c1)n1c([nH]c2=O)c(sc1=S)C(=O)NCC1CCCO1 Show InChI InChI=1S/C22H26N4O4S2/c1-2-3-4-9-23-19(27)13-7-8-15-16(11-13)26-18(25-20(15)28)17(32-22(26)31)21(29)24-12-14-6-5-10-30-14/h7-8,11,14H,2-6,9-10,12H2,1H3,(H,23,27)(H,24,29)(H,25,28)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>6.67E+4	n/a	n/a	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph....				PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2DF6PMF
					More data for this Ligand-Target Pair