BDBM35453 2-(2-furanyl)-4-quinolinecarboxylic acid::2-(2-furyl)cinchoninic acid::2-(furan-2-yl)quinoline-4-carboxylic acid::2-Furan-2-yl-quinoline-4-carboxylic acid::CC-PMLSC-DMA-P117::CHEMBL150924::cid_697640

SMILES: OC(=O)c1cc(nc2ccccc12)-c1ccco1

InChI Key: InChIKey=WWEKTFINADFAEC-UHFFFAOYSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 35453   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual Specificity Protein Phosphatase 1 (Homo sapiens (Human))	BDBM35453 (2-(2-furanyl)-4-quinolinecarboxylic acid | 2-(2-fu...) Show SMILES OC(=O)c1cc(nc2ccccc12)-c1ccco1 Show InChI InChI=1S/C14H9NO3/c16-14(17)10-8-12(13-6-3-7-18-13)15-11-5-2-1-4-9(10)11/h1-8H,(H,16,17)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PCBioAssay	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	7.0	23
CC_PMLSC Curated by PubChem BioAssay					Assay Description The MKP-1 dose response assay SAR support Assay - has been developed to test the activity of a series Analog compounds synthesized by the PMLSC Chemi...				PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q29G5K5D
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM35453 (2-(2-furanyl)-4-quinolinecarboxylic acid | 2-(2-fu...) Show SMILES OC(=O)c1cc(nc2ccccc12)-c1ccco1 Show InChI InChI=1S/C14H9NO3/c16-14(17)10-8-12(13-6-3-7-18-13)15-11-5-2-1-4-9(10)11/h1-8H,(H,16,17)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PCBioAssay	n/a	n/a	2.34E+4	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Molecular Libraries Screening Center Curated by PubChem BioAssay					Assay Description NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: John A. Katzenellenbogen, ...				PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2QJ7FQ3
					More data for this Ligand-Target Pair
Aminoacyl-tRNA synthetase (Homo sapiens (Human))	BDBM35453 (2-(2-furanyl)-4-quinolinecarboxylic acid | 2-(2-fu...) Show SMILES OC(=O)c1cc(nc2ccccc12)-c1ccco1 Show InChI InChI=1S/C14H9NO3/c16-14(17)10-8-12(13-6-3-7-18-13)15-11-5-2-1-4-9(10)11/h1-8H,(H,16,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Cubist Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Aminoacylation activity against human prolyl-tRNA synthetase				Bioorg Med Chem Lett 11: 541-4 (2001) BindingDB Entry DOI: 10.7270/Q2Q23ZH8
					More data for this Ligand-Target Pair
Prolyl-tRNA synthetase (Candida albicans)	BDBM35453 (2-(2-furanyl)-4-quinolinecarboxylic acid | 2-(2-fu...) Show SMILES OC(=O)c1cc(nc2ccccc12)-c1ccco1 Show InChI InChI=1S/C14H9NO3/c16-14(17)10-8-12(13-6-3-7-18-13)15-11-5-2-1-4-9(10)11/h1-8H,(H,16,17)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Cubist Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Aminoacylation activity against Candida albicans prolyl-tRNA synthetase				Bioorg Med Chem Lett 11: 541-4 (2001) BindingDB Entry DOI: 10.7270/Q2Q23ZH8
					More data for this Ligand-Target Pair
dTDP-4-dehydrorhamnose 3,5-epimerase RmlC (Mycobacterium tuberculosis H37Rv)	BDBM35453 (2-(2-furanyl)-4-quinolinecarboxylic acid | 2-(2-fu...) Show SMILES OC(=O)c1cc(nc2ccccc12)-c1ccco1 Show InChI InChI=1S/C14H9NO3/c16-14(17)10-8-12(13-6-3-7-18-13)15-11-5-2-1-4-9(10)11/h1-8H,(H,16,17)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PCBioAssay	n/a	n/a	3.38E+3	n/a	n/a	n/a	n/a	n/a	n/a
PCMD Curated by PubChem BioAssay					Assay Description Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Michael McNeil, Colorado State Universi...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2TD9VRT
					More data for this Ligand-Target Pair