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BDBM354701 Preparation of 4-(((2R,5S)-3-(4-cyano-3-(trifluoromethyl)phenyl)-2-(trifluoromethyl)oxazolidin-5-yl)methoxy)benzoic acid::US9809583, Example 9

SMILES: OC(=O)c1ccc(OC[C@@H]2CN([C@H](O2)C(F)(F)F)c2ccc(c(c2)C(F)(F)F)[N+]([O-])=O)cc1

InChI Key: InChIKey=WRXZFIVGOHHZKX-SUMWQHHRSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 354701   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Androgen Receptor


(Chlorocebus sabaeus (Green monkey) (Cercopithecus ...)		BDBM354701
PNG
(Preparation of 4-(((2R,5S)-3-(4-cyano-3-(trifluoro...)
Show SMILES OC(=O)c1ccc(OC[C@@H]2CN([C@H](O2)C(F)(F)F)c2ccc(c(c2)C(F)(F)F)[N+]([O-])=O)cc1 |r|
Show InChI InChI=1S/C19H14F6N2O6/c20-18(21,22)14-7-11(3-6-15(14)27(30)31)26-8-13(33-17(26)19(23,24)25)9-32-12-4-1-10(2-5-12)16(28)29/h1-7,13,17H,8-9H2,(H,28,29)/t13-,17+/m0/s1
PDB

UniProtKB/TrEMBL

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PC sid
UniChem
US Patent
n/an/a 367n/an/an/an/an/an/a



DONG-A ST CO., LTD.

US Patent


Assay Description
In order to examine binding ability of the agonists of the present invention to androgen receptors, the following in-vitro experiment was performed. ...

US Patent US9809583 (2017)


BindingDB Entry DOI: 10.7270/Q2C82CGC
More data for this
Ligand-Target Pair