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SMILES: Fc1cc(ccc1OC[C@@H]1CN([C@H](O1)C(F)(F)F)c1ccc(C#N)c(c1)C(F)(F)F)C#N

InChI Key: InChIKey=MHXJODFJIPSRTG-KBXCAEBGSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 354703   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Androgen receptor


(Chlorocebus sabaeus (Green monkey) (Cercopithecus ...)		BDBM354703
PNG
(Preparation of 4-((2R,5S)-5-((4-cyano-2-fluorophen...)
Show SMILES Fc1cc(ccc1OC[C@@H]1CN([C@H](O1)C(F)(F)F)c1ccc(C#N)c(c1)C(F)(F)F)C#N |r|
Show InChI InChI=1S/C20H12F7N3O2/c21-16-5-11(7-28)1-4-17(16)31-10-14-9-30(18(32-14)20(25,26)27)13-3-2-12(8-29)15(6-13)19(22,23)24/h1-6,14,18H,9-10H2/t14-,18+/m0/s1
PDB

UniProtKB/TrEMBL

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PC cid
PC sid
UniChem
US Patent
n/an/a 10.5n/an/an/an/an/an/a



DONG-A ST CO., LTD.

US Patent


Assay Description
In order to examine binding ability of the agonists of the present invention to androgen receptors, the following in-vitro experiment was performed. ...

US Patent US9809583 (2017)


BindingDB Entry DOI: 10.7270/Q2C82CGC
More data for this
Ligand-Target Pair