BDBM354708 Preparation of 4-((2S,5R)-5-((R)-2,2,2-trifluoro-1-hydroxyethyl)-2-(trifluoromethyl)oxazolidin-3-yl)-2-(trifluoromethyl)benzonitrile::US9809583, Example 21

SMILES: O[C@H]([C@H]1CN([C@@H](O1)C(F)(F)F)c1ccc(C#N)c(c1)C(F)(F)F)C(F)(F)F

InChI Key: InChIKey=CODCZUURZSYJCY-MXWKQRLJSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 354708   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Androgen Receptor (Chlorocebus sabaeus (Green monkey) (Cercopithecus ...)	BDBM354708 (Preparation of 4-((2S,5R)-5-((R)-2,2,2-trifluoro-1...) Show SMILES O[C@H]([C@H]1CN([C@@H](O1)C(F)(F)F)c1ccc(C#N)c(c1)C(F)(F)F)C(F)(F)F |r| Show InChI InChI=1S/C14H9F9N2O2/c15-12(16,17)8-3-7(2-1-6(8)4-24)25-5-9(10(26)13(18,19)20)27-11(25)14(21,22)23/h1-3,9-11,26H,5H2/t9-,10-,11+/m1/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.06E+3	n/a	n/a	n/a	n/a	n/a	n/a
DONG-A ST CO., LTD. US Patent					Assay Description In order to examine binding ability of the agonists of the present invention to androgen receptors, the following in-vitro experiment was performed. ...				US Patent US9809583 (2017) BindingDB Entry DOI: 10.7270/Q2C82CGC
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