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BDBM354721 Preparation of ((2S,5S)-3-(3-methyl-4-nitrophenyl)-2-(trifluoromethyl)oxazolidin-5-yl)methanol::US9809583, Example 33

SMILES: [O-][N+](=O)c1ccc(OC[C@@H]2CN([C@H](O2)C(F)(F)F)c2ccc(C#N)c(c2)C(F)(F)F)c(F)c1

InChI Key: InChIKey=SLWYEFNOWPJLRG-SUMWQHHRSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 354721   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Androgen Receptor


(Chlorocebus sabaeus (Green monkey) (Cercopithecus ...)		BDBM354721
PNG
(Preparation of ((2S,5S)-3-(3-methyl-4-nitrophenyl)...)
Show SMILES [O-][N+](=O)c1ccc(OC[C@@H]2CN([C@H](O2)C(F)(F)F)c2ccc(C#N)c(c2)C(F)(F)F)c(F)c1 |r|
Show InChI InChI=1S/C19H12F7N3O4/c20-15-6-12(29(30)31)3-4-16(15)32-9-13-8-28(17(33-13)19(24,25)26)11-2-1-10(7-27)14(5-11)18(21,22)23/h1-6,13,17H,8-9H2/t13-,17+/m0/s1
PDB

UniProtKB/TrEMBL

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PC cid
PC sid
UniChem
US Patent
n/an/a 10.4n/an/an/an/an/an/a



DONG-A ST CO., LTD.

US Patent


Assay Description
In order to examine binding ability of the agonists of the present invention to androgen receptors, the following in-vitro experiment was performed. ...

US Patent US9809583 (2017)


BindingDB Entry DOI: 10.7270/Q2C82CGC
More data for this
Ligand-Target Pair