BDBM354722 Preparation of 4-(((2R,5S)-3-(4-cyano-3-(trifluoromethyl)phenyl)-2-(trifluoromethyl)oxazolidin-5-yl)methoxy)-N,N-dimethylbenzamide::US9809583, Example 34
SMILES: CN(C)C(=O)c1ccc(OC[C@@H]2CN([C@@H](O2)C(F)(F)F)c2ccc(C#N)c(C)c2)cc1
InChI Key: InChIKey=DBLPQGJBVILXTL-FPOVZHCZSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Androgen Receptor (Chlorocebus sabaeus (Green monkey) (Cercopithecus ...) | BDBM354722 (Preparation of 4-(((2R,5S)-3-(4-cyano-3-(trifluoro...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 24.1 | n/a | n/a | n/a | n/a | n/a | n/a |
DONG-A ST CO., LTD. US Patent | Assay Description In order to examine binding ability of the agonists of the present invention to androgen receptors, the following in-vitro experiment was performed. ... | US Patent US9809583 (2017) BindingDB Entry DOI: 10.7270/Q2C82CGC | |||||||||||
More data for this Ligand-Target Pair |