BDBM354730 Preparation of 3-(1H-indol-5-yl)-5-(2-(4-methylpiperazin-1-yl)pyridin-4-yl)-1H-pyrrolo[2,3-b]pyridine ::US10485800, Example 7::US9814704, Example 7

SMILES: CN1CCN(CC1)c1cc(ccn1)-c1cnc2[nH]cc(-c3ccc4[nH]ccc4c3)c2c1

InChI Key: InChIKey=SYUTZRZMZRCITO-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 354730   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase 11 (Homo sapiens (Human))	BDBM354730 (Preparation of 3-(1H-indol-5-yl)-5-(2-(4-methylpip...) Show SMILES CN1CCN(CC1)c1cc(ccn1)-c1cnc2[nH]cc(-c3ccc4[nH]ccc4c3)c2c1 Show InChI InChI=1S/C25H24N6/c1-30-8-10-31(11-9-30)24-14-17(4-7-27-24)20-13-21-22(16-29-25(21)28-15-20)18-2-3-23-19(12-18)5-6-26-23/h2-7,12-16,26H,8-11H2,1H3,(H,28,29)	PDB NCI pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
The University of Rochester; Board of Regents of the University of Nebraska US Patent					Assay Description 200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ...				US Patent US10485800 (2019) BindingDB Entry DOI: 10.7270/Q22B91DW
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 11 (Homo sapiens (Human))	BDBM354730 (Preparation of 3-(1H-indol-5-yl)-5-(2-(4-methylpip...) Show SMILES CN1CCN(CC1)c1cc(ccn1)-c1cnc2[nH]cc(-c3ccc4[nH]ccc4c3)c2c1 Show InChI InChI=1S/C25H24N6/c1-30-8-10-31(11-9-30)24-14-17(4-7-27-24)20-13-21-22(16-29-25(21)28-15-20)18-2-3-23-19(12-18)5-6-26-23/h2-7,12-16,26H,8-11H2,1H3,(H,28,29)	PDB NCI pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
The University of Rochester US Patent					Assay Description 200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ...				US Patent US9814704 (2017) BindingDB Entry DOI: 10.7270/Q27H1MRN
					More data for this Ligand-Target Pair