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SMILES: COc1cc(cc(OC)c1OC)-c1cnc2[nH]cc(-c3ccc(nc3)N(C)C)c2c1

InChI Key: InChIKey=ZLGZKSAISQUZPN-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 354742   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase 11 (Homo sapiens (Human))	BDBM354742 (Preparation of N,N-dimethyl-5-(5-(3,4,5-trimethoxy...) Show SMILES COc1cc(cc(OC)c1OC)-c1cnc2[nH]cc(-c3ccc(nc3)N(C)C)c2c1 Show InChI InChI=1S/C23H24N4O3/c1-27(2)21-7-6-14(11-24-21)18-13-26-23-17(18)8-16(12-25-23)15-9-19(28-3)22(30-5)20(10-15)29-4/h6-13H,1-5H3,(H,25,26)	PDB NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
The University of Rochester; Board of Regents of the University of Nebraska US Patent					Assay Description 200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ...				US Patent US10485800 (2019) BindingDB Entry DOI: 10.7270/Q22B91DW
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 11 (Homo sapiens (Human))	BDBM354742 (Preparation of N,N-dimethyl-5-(5-(3,4,5-trimethoxy...) Show SMILES COc1cc(cc(OC)c1OC)-c1cnc2[nH]cc(-c3ccc(nc3)N(C)C)c2c1 Show InChI InChI=1S/C23H24N4O3/c1-27(2)21-7-6-14(11-24-21)18-13-26-23-17(18)8-16(12-25-23)15-9-19(28-3)22(30-5)20(10-15)29-4/h6-13H,1-5H3,(H,25,26)	PDB NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
The University of Rochester US Patent					Assay Description 200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ...				US Patent US9814704 (2017) BindingDB Entry DOI: 10.7270/Q27H1MRN
					More data for this Ligand-Target Pair